In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 29841-69-8, name is (1S,2S)-(-)-1,2-Diphenylethylenediamine, introducing its new discovery. Quality Control of: (1S,2S)-(-)-1,2-Diphenylethylenediamine
On the basis of a kinetic study and other evidence, we propose a mechanism of activation and operation of a highly active system generated from the precatalyst trans-[Fe(CO)(Br)(Ph2PCH2CH=N-((S,S)-C(Ph)H- C(Ph)H)-N=CHCH2PPh2)][BPh4] (2) for the asymmetric transfer hydrogenation of acetophenone in basic isopropanol. An induction period for catalyst activation is observed before the catalytic production of 1-phenethanol. The activation step is proposed to involve a rapid reaction of 2 with excess base to give an ene-amido complex [Fe(CO)(Ph 2PCH2CH=N-((S,S)-C(Ph)H-C(Ph)H)-NCH=CHPPh 2)]+ (Fep) and a bis(enamido) complex Fe(CO)(Ph2PCH=CH-N-(S,S-CH(Ph)CH(Ph))-N-CH=CHPPh2) (5); 5 was partially characterized. The slow step in the catalyst activation is thought to be the reaction of Fep with isopropoxide to give the catalytically active amido-(ene-amido) complex Fea with a half-reduced, deprotonated PNNP ligand. This can be trapped by reaction with HCl in ether to give, after isolation with NaBPh4, [Fe(CO)(Cl)(Ph 2PCH2CH2N(H)-((S,S)-CH(Ph)CH(Ph))-N=CHCH 2PPh2)][BPh4] (7) which was characterized using multinuclear NMR and high-resolution mass spectrometry. When compound 7 is treated with base, it directly enters the catalytic cycle with no induction period. A precatalyst with the fully reduced P-NH-NH-P ligand was prepared and characterized by single crystal X-ray diffraction. It was found to be much less active than 2 or 7. Reaction profiles obtained by varying the initial concentrations of acetophenone, precatalyst, base, and acetone and by varying the temperature were fit to the kinetic model corresponding to the proposed mechanism by numerical simulation to obtain a unique set of rate constants and thermodynamic parameters.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 29841-69-8 is helpful to your research. Quality Control of: (1S,2S)-(-)-1,2-Diphenylethylenediamine
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI