Day: September 3, 2020

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.17217-57-1,4,4′-Dimethoxy-2,2′-bipyridine,as a common compound, the synthetic route is as follows.

General procedure: [Cu-(MeCN)4]PF6 (74 mg, 0.20 mmol) was added to TolBINAP(135 mg, 0.20 mmol) in 2 mL CH2Cl2. Then, bpy (31 mg, 0.20mmol) was added. The yellow reaction mixture was stirred for90 minutes at room temperature. Diethyl ether (25 mL) wasadded to the solution to precipitate the product as a yellowsolid, which was filtered and dried in vacuum.

17217-57-1, The synthetic route of 17217-57-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Nishikawa, Michihiro; Tsuji, Masakata; Ohishi, Tomoyuki; Tsubomura, Taro; Bulletin of the Chemical Society of Japan; vol. 90; 7; (2017); p. 798 – 800;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

A solution of (No.5-Ind) Mo (CO) 2 (3-C3H5) (0.20g, 0.65 mmol) in CH2C12 was treated with HBF4. Et2O (1 eq. ). After 10 minutes dme was added in excess and the reaction was left for 15 minutes. 0.27 g (0.8 mmol) of 4, 7-diphenil-1, 10-phenantroline were added and the reaction was left for 2 hours at room temperature. After concentration to about 5 ml and addition of Et20, a ruby complex precipitated. The mixture was filtered and the residue recrystallized from CH2CI2/Et2O (razz 90%). A drawing of the structure and physical data are given in Table 1., 1662-01-7

The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; IBET-INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA; WO2005/87783; (2005); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

103946-54-9, 4′-Methyl-[2,2′-bipyridine]-4-carboxylic acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

EXAMPLE. Peptide Synthesis. The collagen-mimetic peptide H-byp, NH2-(Pro-Hyp-Gly)4-(Pro-Lys(Mtt)-Gly)-(Pro-Hyp-Gly)4-COOH, was synthesized by standard solid phase synthesis on a rink amide Chem Matrixresin. In the manual synthesis, 3 equivalents of Fmoc-amino acids were treated with HBTU (3 equiv.) and diisopropylethylamine(DIEA) (2 equiv) in an NMP solution. For the N-terminal acetylation, the resin was treated with acetic anhydrideand DIEA in DMF for 1 hr. The Mtt protecting group was removed using as described above using 1.8% TFA in DCM.The resin was treated with 2,2?-bipyridine-4,4?-carboxylic acid (3 equiv.), HBTU (3 equiv.), and DIEA (3 equiv.) in NMP.The peptide was cleaved from the resin by treatment for 2 h with TFA/TIPS/H2O (95:2.5:2.5), followed by precipitationwith diethyl ether.

103946-54-9, As the paragraph descriping shows that 103946-54-9 is playing an increasingly important role.

Reference£º
Patent; Purdue Research Foundation; CHMIELEWSKI, Jean, A.; PIRES, Marcos, M.; PRZYBYLA, David, E.; (74 pag.)EP2300033; (2016); B1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

The [Ru(dpphen)3]Cl2 is synthesized using literature method [35] . RuCl3?3H2O (1 mmol) and 4,7-diphen-1,10-phenanthroline (3 mmol) is taken in ethylene glycol under nitrogen atmosphere and heated to reflux for 72 h and the crude product is chromatographed using silica gel. The solution on evaporation yielded orange red crystals. Yield = 85% ESI-MS (m/z) 548.6496 (M-2Cl- doubly charged species)., 1662-01-7

As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

Reference£º
Article; Babu, Eththilu; Muthu Mareeswaran, Paulpandian; Singaravadivel, Subramanian; Bhuvaneswari, Jayaraman; Rajagopal, Seenivasan; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 130; (2014); p. 553 – 560;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4479-74-7,2,2-Bipyridine-6,6-dicarboxylic Acid,as a common compound, the synthetic route is as follows.

A mixture of Tb(NO3)3¡¤6H2O (0.045 g, 0.10 mmol), H2bpdc (0.024 g, 0.10 mmol) in distilled water (10 mL) that adjusted the pH value to 2.5 with 0.5 mol L-1 NaOH aqueous solution. It was then sealed in a 25 mL Teflon reactor and heated at 160 C for 72 h, and then cooled to ambient temperature at a rate of ca.2 C h-1 to give colorless block crystals of 7, yield: 57% based on H2bpdc. Elemental analysis: Anal. Calc. for C36H36N6O21Tb2: C, 35.63; N, 6.92; H, 2.99. Found: C, 35.91; N, 6.66; H, 3.07%. IR (KBr, cm-1): 3108 (w), 1638 (vs), 1466 (s), 1421 (vs), 1315 (s), 1276 (s), 1189 (s), 1160 (s), 1085 (m), 919 (m), 861 (s), 796 (s), 771 (vs), 718 (s), 674 (s), 640 (s), 592 (m), 485 (m), 437(m).

4479-74-7, The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ren, Ya-Lan; Wang, Fei; Hu, Huai-Ming; Chang, Zhuguo; Yang, Meng-Lin; Xue, Ganglin; Inorganica Chimica Acta; vol. 434; (2015); p. 104 – 112;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.112881-51-3,4′-(4-Pyridyl)-2,2′:6′,2”-terpyridine,as a common compound, the synthetic route is as follows.

Single crystals of 3 were prepared by adding 0.5 mmol (0.149 g) of zinc nitrate hexahydrate, 1mmol of sodium perchlorate (0.122 g) and 0.5mmol (0.156 g) of pyterpy to 20mL of distilled water. This mixture was transferred to a hydrothermal bomb and placed at 150 C for 48 h. The yellow crystals were obtained by cooling the bomb to room temperature for 12 h. The crystals were washed with methanol and air dried. m.p. > 300 C. Yield: 0.343 g (73%). IR (selected bands; in cm1): 623 (m), 791 (m), 1089 (vs), 1412(m), 1472 (m), 1599 (m), 3449 (b). Anal. calc for ZnC40H34N8Cl2O11: C, 51.14; H, 3.65; N, 11.94%. Found; C, 50.82; H, 3.68; N, 11.92%.

112881-51-3, 112881-51-3 4′-(4-Pyridyl)-2,2′:6′,2”-terpyridine 11438308, acatalyst-ligand compound, is more and more widely used in various.

Reference£º
Article; Mehrani, Azadeh; Morsali, Ali; Ebrahimpour, Parisa; Journal of Coordination Chemistry; vol. 66; 5; (2013); p. 856 – 867;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1662-01-7, 4,7-Diphenyl-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,1662-01-7

General procedure: A mixture of CuBr (28.7mg, 0.2mmol) and dppp (82.5mg, 0.2mmol) with an excess of batho (66.5mg, 0.2mmol) were dissolved in CH2Cl2 (5mL) and CH3OH (5mL) solution, stirred at room temperature for 6h. The insoluble residues were removed by filtration, and the filtrate was evaporated slowly at room temperature to yield yellow crystalline products.

As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

Reference£º
Article; Yu, Xiao; Fan, Weiwei; Wang, Guo; Lin, Sen; Li, Zhongfeng; Liu, Min; Yang, Yuping; Xin, Xiulan; Jin, Qionghua; Polyhedron; vol. 157; (2019); p. 301 – 309;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.17217-57-1,4,4′-Dimethoxy-2,2′-bipyridine,as a common compound, the synthetic route is as follows.

General procedure: [Cu-(MeCN)4]PF6 (74 mg, 0.20 mmol) was added to TolBINAP(135 mg, 0.20 mmol) in 2 mL CH2Cl2. Then, bpy (31 mg, 0.20mmol) was added. The yellow reaction mixture was stirred for90 minutes at room temperature. Diethyl ether (25 mL) wasadded to the solution to precipitate the product as a yellowsolid, which was filtered and dried in vacuum.

17217-57-1, As the paragraph descriping shows that 17217-57-1 is playing an increasingly important role.

Reference£º
Article; Nishikawa, Michihiro; Tsuji, Masakata; Ohishi, Tomoyuki; Tsubomura, Taro; Bulletin of the Chemical Society of Japan; vol. 90; 7; (2017); p. 798 – 800;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.148332-36-9,[2,2′:6′,2”-Terpyridine]-4′-carboxylic acid,as a common compound, the synthetic route is as follows.

Synthesized according to the route shown in Figure 6.Taking tert-butoxycarbonylglycine (0.35 g, 2 mmol) and aminothiazole compoundTz-NH2 (0.47 g, 2 mmol),Dicyclohexylcarbodiimide DCC (0.41 g, 2 mmol),30 mL of N,N-dimethylformamide was stirred at room temperature for 3 hours.The solvent was evaporated under reduced pressure to give a white solid. The solid was dissolved in 20 mL of dichloromethane and then added with trifluoroAcetic acid (1.03 g, 9 mmol) was stirred for 1 hr. Add N,N-dimethylformamide30 mL dissolved, added tpyCOOH (0.55 g, 2 mmol), dicyclohexylcarbodiimide DCC (0.41 g, 2 mmol), 30It was stirred at room temperature for 3 hours. The solvent was evaporated under reduced pressure, washed with water and dried in vacuo to give a white solid. Production volume 0.99g, yield 90percent. Precursor complex [Ru(tpy)Cl3] (0.79 g, 1.7 mmol) and ligand tpyL3 (0.99 g, 1.8)Methyl) 50 mL of ethylene glycol methyl ether and 0.5 mL of 4-ethylmorpholine were added to the flask and refluxed for 4 hours. Cool to room temperature, filter,To the filtrate was added saturated KPF6 (815 mg, 5 mmol), and the precipitate was precipitated.It was then vacuum dried to give a crude product. Chromatography on silica gel column, eluting with a mixture of acetonitrile and methanol (volume ratio 2:1)The color component gives the target terpyridine pyridinium (II) complex RuTz3. The yield was 1.43 g and the yield was 72percent., 148332-36-9

The synthetic route of 148332-36-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Yunnan University; Gao Feng; Ma Guolan; Bi Xudan; (15 pag.)CN109096339; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI