Day: April 11, 2022

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called DNA binding properties of novel cytotoxic gold(III) complexes of terpyridine ligands: the impact of steric and electrostatic effects, published in 2006-09-30, which mentions a compound: 89972-77-0, mainly applied to gold terpyridine functionalized preparation antitumor activity DNA binding; steric effect DNA binding gold complex functionalized terpyridine, Formula: C22H17N3.

Four Au(III) complexes of terpyridine derivatives In+ (R = H, 2-naphthyloxy, n = 2; R = PPh3, n = 3; R = NHCH2CH2SO3Na, n = 2) were synthesized and characterized by spectroscopic methods. In vitro data demonstrated that all of them showed higher cytotoxicity than cisplatin against the human nonsmall-cell lung cancer cell line (A-549), the human stomach carcinoma cell line (SGC-7901), the human cervix carcinoma cell line (HELA), the human colon carcinoma cell line (HCT-116), the human liver carcinoma cell line (BEL-7402), the murine leukemia cell line (P-388) and the human acute promyelocytic leukemia cell line (HL-60). Complex I (R = PPh3) exhibits the highest activity, with growth inhibition rates of over 80% at 10-8 mol L-1 against the A-549, HCT-116 and HELA tumor cell lines. The free ligands are also very cytotoxic against the cell lines tested. Complexes I are stable in aqueous solution for 2 days in the presence of the biol. reducing agent glutathione. The inductively coupled plasma mass spectrometry data showed that DNA isolated from cells treated with complexes I (R = H, PPh3) contained Au with Au-to-nucleotide ratios of ∼1:6,400 and 1:4,900, resp. Fluorescence titration, UV and CD analyses proved that the steric and electrostatic effects of the ligand remarkably influence the interactions of their Au(III) complexes with DNA. The DNA binding ability of the complexes was correlated with their cytotoxicity, which could potentially provide a new rationale for the future design of terpyridine-based metal complexes with antitumor potential.

In addition to the literature in the link below, there is a lot of literature about this compound(4-(p-Tolyl)-2,2:6,2-terpyridine)Formula: C22H17N3, illustrating the importance and wide applicability of this compound(89972-77-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Reference of 4-(p-Tolyl)-2,2:6,2-terpyridine. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 4-(p-Tolyl)-2,2:6,2-terpyridine, is researched, Molecular C22H17N3, CAS is 89972-77-0, about Self-assembly of nanocrystalline tetra-terpyridine complexes: from molecules to mesoscopic objects.

We report the properties of a shape-persistent tetra-terpyridine ligand whose coordination to transition metal ions guides its three-dimensional self-assembly in two steps: at first, nanoscale objects form, which with time, self-assemble into micrometer structures. This work highlights the potential for control of the mol. self-assembly of mols. on the nanoscale, and the successive self-assembly of the formed supramol. nanosystems to yield mesoscopic objects.

In addition to the literature in the link below, there is a lot of literature about this compound(4-(p-Tolyl)-2,2:6,2-terpyridine)Reference of 4-(p-Tolyl)-2,2:6,2-terpyridine, illustrating the importance and wide applicability of this compound(89972-77-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 89972-77-0, is researched, SMILESS is CC1=CC=C(C2=CC(C3=NC=CC=C3)=NC(C4=NC=CC=C4)=C2)C=C1, Molecular C22H17N3Journal, Crystal Growth & Design called Unusual 2D → 3D Polycatenane Frameworks Based on 1D → 2D Interdigitated Layers: From Single Crystals to Submicrometer Fibers with Enhanced UV Photocatalytic Degradation Performances, Author is Guo, Jiao; Ma, Jian-Fang; Li, Jun-Jie; Yang, Jin; Xing, Shuang-Xi, the main research direction is crystal structure cobalt manganese zinc cadmium tolylterpyridine tetracarboxylate; transition metal terpyridine carboxylate MOF preparation photocatalytic activity; methylene blue photocatalytic degradation catalyzed transition metal tolylterpyridine tetracarboxylate.HPLC of Formula: 89972-77-0.

Four unusual isomorphous metal-organic frameworks, [M2(L1)(L2)2] (M = Co for 1, Mn for 2, Zn for 3, and Cd for 4), where H4L1 = tetrakis[4-(carboxyphenyl)-oxamethyl]methane acid and L2 = 4-tolyl-2,2′:6′,2”-terpyridine, were synthesized under hydrothermal conditions. Their structures were determined by single-crystal x-ray diffraction analyses and further characterized by IR spectra, elemental analyses, powder X-ray diffraction, UV-visible absorption spectra, and optical energy gaps. In 1-4, the metal atoms are linked by the L1 anions to yield a chain with a loop. Every loop of each chain is penetrated by two L2 ligand rods from the two nearest chains, resulting in an unusual 1-dimensional → 2-dimensional interdigitated network. In the 2-dimensional interdigitated network, there exist weak π-π interactions between pyridyl groups of L2 ligands. If the π-π interactions are regarded as linkers, the 2-dimensional interdigitated network belongs to an uneven (3,4)-connected layer. Also, each individual (3,4)-connected layer is polycatenated with an infinite number of other perpendicular layers, yielding an unusual 2-dimensional → 3-dimensional polycatenane framework. The luminescent properties of compounds 3 and 4 were studied. Compounds 1-4 exhibit photocatalytic activities for MB degradation under UV irradiation Submicrometer fiber 1′ shows high photocatalytic efficiency for MB degradation with respect to its corresponding macroscaled crystalline 1.

In addition to the literature in the link below, there is a lot of literature about this compound(4-(p-Tolyl)-2,2:6,2-terpyridine)HPLC of Formula: 89972-77-0, illustrating the importance and wide applicability of this compound(89972-77-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Okabe, Masami; Sun, Ruen Chu; Tam, Steve Y. K.; Todaro, Louis J.; Coffen, David L. published the article 《Synthesis of the dideoxynucleosides “”ddC”” and “”CNT”” from glutamic acid, ribonolactone, and pyrimidine bases》. Keywords: dideoxycytidine; cytidine dideoxy; deoxycyanothymidine; thymidine deoxycyano; crystal structure cyanohydroxymethyltetrahydrofuranone; mol structure cyanohydroxymethyltetrahydrofuranone.They researched the compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one( cas:32780-06-6 ).Recommanded Product: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:32780-06-6) here.

2,3-Dideoxyribose in suitably protected form was prepared from L-glutamic acid and coupled with silylated cytosine to give a mixture of the α- and β-anomers of 2′,3′-dideoxycytidine. The anomer ratio depended on the Lewis acid used in the coupling, with EtAlCl2 favoring the β-anomer ddC (I), a potent anti-HIV drug. Conjugate addition of cyanide to a 4-[(silyloxy)methyl]butenolide prepared from D-ribonolactone gave a mixture of (racemic) α- and β-3-cyanobutyrolactones. Both isomers were reduced to lactols and coupled with thymine to give α/β-anomer pairs. The α-cyano lactone, the structure of which was established by x-ray crystallog. of II, afforded an authentic sample of the putative (but in fact inactive) anti-HIV substance known in AIDS research as CNT (III).

In addition to the literature in the link below, there is a lot of literature about this compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Recommanded Product: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, illustrating the importance and wide applicability of this compound(32780-06-6).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Kawamoto, Naoki; Hu, Yongxing; Kuwahara, Yutaka; Ihara, Hirotaka; Takafuji, Makoto researched the compound: 11-Bromoundecanoic acid( cas:2834-05-1 ).Product Details of 2834-05-1.They published the article 《A molecular shape recognitive HPLC stationary phase based on a highly ordered amphiphilic glutamide molecular gel》 about this compound( cas:2834-05-1 ) in Nanomaterials. Keywords: amphiphilic glutamide mol gel shape HPLC stationary phase; high performance liquid chromatography (HPLC); highly-oriented structure; molecular gels; phenolic compounds; stereo isomers; steroids. We’ll tell you more about this compound (cas:2834-05-1).

Chiral glutamide-derived lipids form self-assembled fibrous mol. gels that can be used as HPLC organic phases. In this study, HPLC separation efficiency was improved through the addition of branched amphiphilic glutamide lipids to the side chains of a terminally immobilized flexible polymer backbone. Poly(4-vinylpyridine) with a trimethoxysilyl group at one end was grafted onto the surface of porous silica particles (Sil-VP15, polymerization degree = 15), and the pyridyl side chains were quaternized with a glutamide lipid having a bromide group (BrG). Elemental anal. indicated that the total amount of the organic phase of the prepared stationary phase (Sil-VPG155) was 38.0 wt%, and the quaternization degree of the pyridyl groups was determined to be 32.5%. Differential scanning calorimetric anal. of a methanol suspension of Sil-VPG15 indicated that the G moieties formed a highly ordered structure below the phase transition temperature even on the silica surface, and the ordered G moieties exhibited a gel-to-liquid crystalline phase transition. Compared with a com. available octadecylated silica column, the Sil-VPG15 stationary phase showed high selectivity toward polycyclic aromatic hydrocarbons, and particularly excellent separations were obtained for geometrical and positional isomers. Sil-VPG15 also showed highly selective separation for phenol derivatives, and bio-related mols. containing phenolic groups such as steroids were successfully separated These separation abilities are probably due to multiple interactions between the elutes and the highly ordered functional groups, such as the pyridinium and amide groups, on the highly ordered mol. gel having self-assembling G moieties.

In addition to the literature in the link below, there is a lot of literature about this compound(11-Bromoundecanoic acid)Product Details of 2834-05-1, illustrating the importance and wide applicability of this compound(2834-05-1).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Chen, Jie; He, Xian; Zhang, Xuyan; Chen, Yi; Zhao, Lu; Su, Jiaen; Qu, Shengbin; Ji, Xinwei; Wang, Tao; Li, Zhenjie; He, Chenggang; Zeng, Erqing; Jin, Yan; Lin, Zhonglong; Zou, Congming published an article about the compound: (S)-3-(Piperidin-2-yl)pyridine( cas:494-52-0,SMILESS:C1(C=NC=CC=1)[C@@H]1CCCCN1 ).Category: catalyst-ligand. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:494-52-0) through the article.

Heated tobacco (Nicotiana tabacum L.) products develop rapidly because of its low toxicity. In order to evaluate the industrial applicability of the existing types of characteristic tobacco as raw materials for heated tobaccos, this research ascertained differences in the main chem. compositions in tobacco leaves from different types to establish a relationship between chem. composition and sensory evaluation to select types suitable for producing heated tobaccos. Nine tobacco types (K326, Yunyan 97, Cherry-red tobacco, Han tobacco, Dao tobacco, Tiandeng tobacco, Sun-cured yellow tobacco, fresh-cut tobacco, and aromatic tobacco) planted in Yunnan Province, China were selected. Their sensory quality was evaluated by the method for sensory evaluation of heated tobaccos and chem. composition and content of aroma substances in tobacco leaves were determined In the evaluation of sensory quality of heated tobaccos, the total score of Tiandeng tobacco was significantly higher than those of the other types, followed by Cherry-red tobacco and K326; There were significant differences in chem. composition in the nine tobacco types and the total alkaloid content in Cherry-red tobacco was notably higher than in the other tobacco types. The amounts of total sugar, reducing sugar, and starch in Han tobacco were significantly lower than other types, while the amounts of total nitrogen, potassium oxide, chloride ions, and protein were much higher than in the other tobacco types. The total amounts of polyphenols and aroma compounds in fresh-cut tobacco were significantly higher than in the other tobacco types. The contents of nornicotine, neonicotine, anatabine, and total alkaloid showed a significant pos. correlation with the total sensory evaluation score. The contents of nicotyrine and 2,3-bipyridine were significantly and neg. correlated with the total sensory evaluation score. A remarkable neg. correlation was found between starch content and score on irritation. Furthermore, the amounts of neochlorogenic acid, chlorogenic acid, caffeic acid, and total polyphenols were significantly and pos. correlated with the total sensory evaluation score. The amounts of aldehydes and phenolic compounds had a significant neg. correlation, while the amount of olefin compounds had a significant pos. correlation, with the total sensory evaluation score. These chems. in tobacco leaves can be used as in analyses screening of other suitable tobacco types, and as reference standards for selecting tobacco raw materials suitable for high-quality heated tobaccos.

In addition to the literature in the link below, there is a lot of literature about this compound((S)-3-(Piperidin-2-yl)pyridine)Category: catalyst-ligand, illustrating the importance and wide applicability of this compound(494-52-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Zheng, Chao; Wang, Guang-Zu; Shang, Rui published the article 《Catalyst-free decarboxylation and decarboxylative Giese additions of alkyl carboxylates through photoactivation of electron donor-acceptor complex》. Keywords: alkyl carboxylate preparation green chem; acyloxy phthalimide preparation alkene photochem Giese addition; pyridinium salt preparation alkene photochem Giese addition.They researched the compound: 11-Bromoundecanoic acid( cas:2834-05-1 ).Name: 11-Bromoundecanoic acid. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:2834-05-1) here.

A catalyst-free method to perform decarboxylative conjugated addition and hydrodecarboxylation of aliphatic N-(acyloxy) phthalimides e.g., I (redox active esters, RAEs) through photoactivation of electron-donor-acceptor (EDA) complex with Hantzsch ester (HE) in N,N-dimethylacetamide (DMA) solution was reported. The reactions present a green method to decarboxylatively construct carbon-carbon bond and to perform hydrodecarboxylation with broad substrate scope and functional group tolerance under mild blue light irradiation condition without recourse of popularly used photo-redox catalysts.

In addition to the literature in the link below, there is a lot of literature about this compound(11-Bromoundecanoic acid)Name: 11-Bromoundecanoic acid, illustrating the importance and wide applicability of this compound(2834-05-1).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Redox-Responsive Pickering Emulsions Stabilized by Silica Nanoparticles and Ferrocene Surfactants at a Very Low Concentration, published in 2019-10-07, which mentions a compound: 2834-05-1, mainly applied to green pickering emulsion silica nanoparticle ferrocene surfactant stabilized, Recommanded Product: 2834-05-1.

Here, we describe a redox-responsive Pickering emulsion stabilized by silica nanoparticles and a ferrocene surfactant (FcCOC10N) at a concentration as low as 0.01 mM (≈0.005 cmc). The emulsions are stable and resistant to coalescence for more than one month. The ferrocene group in the structure of FcCOC10N can be reversibly switched between its oxidized and reduced forms by redox reactions, which would alter the amphiphilic properties of the surfactant. Consequently, the emulsion can be switched between ′′on′′ (stable) and ′′off′′ (unstable) states through electrochem. reactions without adding addnl. chems. or changing the particle/surfactant concentration Moreover, the Pickering emulsifier composed of the surfactant and the nanoparticles can be recovered and reused after removal of the original oil. It offers a new platform that provides green and sustainable operation for separation and reuse of the emulsifier in potential applications, such as biphasic catalysis and oil transportation. Redox-responsive Pickering emulsions were prepared using silica nanoparticles and a ferrocene surfactant, in which the emulsifier can be recycled and reused without addnl. chems. or expensive equipment.

In addition to the literature in the link below, there is a lot of literature about this compound(11-Bromoundecanoic acid)Recommanded Product: 2834-05-1, illustrating the importance and wide applicability of this compound(2834-05-1).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Xiang, Xian-Ming; Qian, Dong-Jin; Li, Fu-You; Chen, Hai-Tao; Liu, Hong-Guo; Huang, Wei; Feng, Xu-Sheng researched the compound: 4-(p-Tolyl)-2,2:6,2-terpyridine( cas:89972-77-0 ).Synthetic Route of C22H17N3.They published the article 《Fabrication of europium complexes with 4′-(4-methylphenyl)-2,2′:6′,2”-terpyridine and 4,4′-dinonyl-2,2′-dipyridyl at the air-water interface and their emission properties in Langmuir-Blodgett films》 about this compound( cas:89972-77-0 ) in Colloids and Surfaces, A: Physicochemical and Engineering Aspects. Keywords: europium complex methylphenyl terpyridine Langmuir Blodgett film fluorescence; dinonyl dipyridyl europium complex Langmuir Blodgett film fluorescence. We’ll tell you more about this compound (cas:89972-77-0).

Ternary Eu complexes were formed at the air-H2O interface mediated by monolayers of 4,4′-dinonyl-2,2′-dipyridyl (DNDPy) and 4′-(4-methylphenyl)-2,2′:6′,2”-terpyridine (MPTPy). A saturated Eu(TTA)3 (TTA: theonyltrifluoroacetone) aqueous solution was used as subphase, on the surface of which condensed DNDPy and MPTPy monolayers could be stabilized. The DNDPy-/MPTPy-Eu(TTA)3 layers were transferred onto either hydrophobic or hydrophilic substrate surfaces by Langmuir-Blodgett (LB) method. Fluorescence spectra showed several sharp peaks corresponding to Eu3+ emissions from 5D1 → 7F1 (535 nm) and 5D0 → 7F0,1,2,3 (580, 595, 612 and 650 nm). A relative stronger emission from 5D1 → 7F1 to that from 5D0 → 7F2 was recorded for the LB films of DNDPy-Eu(TTA)3 complex. Compared with that in solution, longer fluorescence lifetime was observed for the complexes in the LB films.

In addition to the literature in the link below, there is a lot of literature about this compound(4-(p-Tolyl)-2,2:6,2-terpyridine)Synthetic Route of C22H17N3, illustrating the importance and wide applicability of this compound(89972-77-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Wang, Jianhua; Hanan, Garry S. published an article about the compound: 4-(p-Tolyl)-2,2:6,2-terpyridine( cas:89972-77-0,SMILESS:CC1=CC=C(C2=CC(C3=NC=CC=C3)=NC(C4=NC=CC=C4)=C2)C=C1 ).Product Details of 89972-77-0. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:89972-77-0) through the article.

A facile one-pot synthesis of 4′-aryl-2,2′:6′,2”-terpyridines from aryl aldehydes and 2-acetylpyridine is presented. The synthesis of terpyridines incorporating sterically hindered aryl groups, such as the 9-anthracenyl group, can also be readily synthesized using this method.

In addition to the literature in the link below, there is a lot of literature about this compound(4-(p-Tolyl)-2,2:6,2-terpyridine)Product Details of 89972-77-0, illustrating the importance and wide applicability of this compound(89972-77-0).

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI