65355-14-8, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 65355-14-8, Name is (R)-5,5′,6,6′,7,7′,8,8′-Octahydro[1,1′-binaphthalene]-2,2′-diol, molecular formula is C20H22O2. In a Article, authors is Novikov, Roman£¬once mentioned of 65355-14-8
Enantioselective olefin epoxidation using axially chiral biaryl azepinium salts as catalysts. Rapid in-situ screening and origin of the stereocontrol
To unravel the origin of the stereocontrol in epoxidation reactions of unfunctionalized alkenes by diastereomeric biaryl oxaziridinium salts, two series of novel iminium cations were prepared. These moieties combine (R a)-dimethylbiphenyl or (Ra)-5,5?,6,6?,7, 7?,8,8?-octahydrobinaphthyl cores with chiral exocyclic appendages derived from commercially available (S)- or (R)-3,3-dimethylbutan-2-amine and (S)- or (R)-1-phenylpropan-1-amine. Under biphasic enantioselective olefin epoxidation conditions, in-situ generated bromide salts of these derivatives have displayed similar or better asymmetric efficiency than the classical binaphthyl derivatives. A structural analysis was performed in search of a correlation between the origin of the stereocontrol/level of enantioselectivity in the products, and dihedral angles around the biaryl twist of the catalysts.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. 65355-14-8, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 65355-14-8, in my other articles.
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI