A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, 20439-47-8, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 20439-47-8, Name is (1R,2R)-Cyclohexane-1,2-diamine, molecular formula is C6H14N2. In a Article, authors is Karame, Iyad£¬once mentioned of 20439-47-8
New ruthenium catalysts containing chiral Schiff bases for the asymmetric hydrogenation of acetophenone
A series of new chiral N4-Schiff bases, containing amine or sulfonamide functionalities has been synthesized. Coupled with ruthenium catalysts, these Schiff bases induce interesting results in the hydrogenation of acetophenone: complete conversion and 76% ee were obtained with the catalytic system Ru(PPh3)3Cl2/(1R,2R)-N,N?-bis-(2- p-tosylaminobenzylidene)-1,2-diphenylethylenediamine. A very important phosphine co-ligand effect was observed on both activity and enantioselectivity of the catalysts. However, without the co-ligand, we obtained an enantioselectivity for the (R)-enantiomer, whereas with nonchiral co-ligand an enantioselectivity for the (S)-enantiomer was observed.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 20439-47-8, help many people in the next few years.20439-47-8
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI