With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
0.34 mmol dichloro bridged intermediate and 1.0 g4,7-diphenyl-1,10-phenanthroline was dissolved in 40 mL of ethylene glycol.The reaction system is protected with nitrogen.Stirred at 130 C for 15 hours.After cooling to room temperature, the reaction solution was poured into a 100 mL flask.A saturated NH4PF6 aqueous solution was added thereto with stirring.A large amount of solids precipitated,filter,Wash with a small amount of deionized water,70 C vacuum drying for 5 hours,The crude product is chromatographed on a chromatographic column.a dark brown solidYield 50%.
As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.
Reference£º
Patent; Tsinghua University; Qiao Juan; Xin Lijun; (29 pag.)CN104804045; (2018); B;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI