Chemistry is an experimental science, category: catalyst-ligand, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 943757-71-9, Name is (R)-2-(Diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine
A 3 – benzyloxymethyl – 4 – aryl – 5 – nitro – 1 – formyl cyclohexene preparation method (by machine translation)
The invention relates to a 3 – benzyloxymethyl – 4 – aryl – 5 – nitro – 1 – formyl cyclohexene preparation method, the 3 – benzyloxymethyl – 4 – aryl – 5 – nitro – 1 – formyl cyclohexene structure as shown in formula I: In the formula R is a substituted, disubstituted, trisubstituted and four substituted halogen, nitro, amino, 1 – 10 carbon alkyl or 1 – 10 alkoxy; preparation method comprises the following: the 3 – benzyloxy propionaldehyde, (E)- (2 – nitroethylene) aromatic compound with a secondary amine and solvent mixed, for 0 – 25 C reaction 1 – 24 hours later, by washing, extraction, separation, to obtain 3 – benzyloxymethyl – 4 – aryl – 5 – nitro – 1 – formyl cyclohexene; The present invention provides synthetic method is simple in operation, mild reaction conditions, does not need to be water-free, oxygen-free processing, does not need to be low-temperature refrigeration. Yield of the object product, the resulting of the target product as a single isomer, in optical pure catalyst catalyzes the reaction of the enantioselectivity is greater than 99% ee. (by machine translation)
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. category: catalyst-ligand, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 943757-71-9, in my other articles.
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI