Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products, Quality Control of Indene, 95-13-6, Name is Indene, molecular formula is C9H8, belongs to catalyst-ligand compound. In a document, author is Mikherdov, Alexander S., introduce the new discover.
Reaction mechanism of regioisomerization in binuclear (diaminocarbene) Pd-II complexes
A series of binuclear Pd-II carbene complexes were synthesized via the treatment of cis-[PdCl2(CNXyl)(2)] (1) with benzo-1,3-thiazol-2-amines (2-6) and structurally characterized. In every case the reaction leads to the mixture of two regioisomers, which are able to interconvert. The study of the regioisomerization of the binuclear diamino-carbene species showed that it is a first-order reaction, that is, it occurs intramolecularly, and was analyzed with the Hammett function. Electron-withdrawing substituents in the benzothiazole moiety of the complexes as well as increasing the solvent polarity accelerate the reaction. The solvent donor strength correlates less well with the isomerization rates. Based on the obtained activation parameters the studied regioisomerization could be defined as the interchange/dissociative process type. A combined approach including kinetic and mass spectrometric studies allowed the conclusion that the rate-determining step of the isomerization is breaking the carbon-nitrogen bond in the carbene fragment of the binuclear complex.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 95-13-6. Quality Control of Indene.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI