With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
The complex was synthesized by adapting to literature methods7, 14 of an analogous compound.[Ru(benzene)Cl2]2 (0.75g, 1.5 mmol) and 4,7-diphenyl-1,10-phenanthroline (1.0g, 3.0 mmol)were dissolved in 70 mL methanol. The solution was degassed for 15 minutes before refluxingfor 3 h under argon. The reaction was filtered while hot using a fine frit. The filtrate wasevaporated to near dryness under reduced pressure. The solid was then dissolved in small amountof methanol and precipitated twice in DEE (2 x 100 mL). The solid was dried to yield a lightyellow solid (1.7 g, yield 97%). 1H NMR (500MHz, RT, DMSO-d6): delta (ppm) 10.1 (2H, d, J =5.5 Hz), 8.16 (2H, d, J = 5.5 Hz), 8.12 (2H, s) 7.66-7.74 (10H, m) 6.36 (6H, s). UV-Vis inDMF: lambdamax. 294 nm, and a shoulder at 343 nm.
As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.
Reference£º
Article; Kosgei, Gilbert K.; Livshits, Maksim Y.; Canterbury, Theodore R.; Rack, Jeffery J.; Brewer, Karen J.; Inorganica Chimica Acta; vol. 454; (2017); p. 67 – 70;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI