Chemistry is an experimental science, Safety of H-Pro-NH2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 7531-52-4, Name is H-Pro-NH2, molecular formula is C5H10N2O, belongs to catalyst-ligand compound. In a document, author is Wang, Dan.
Dual Palladium/Scandium Catalysis toward Rotationally Hindered C3-Naphthylated Indoles from beta-Alkynyl Ketones and o-Alkynyl Anilines
Main observation and conclusion A new dual palladium/scandium catalysis starting from beta-alkynyl ketones and o-alkynyl anilines is reported for the first time, leading to the atom-economic synthesis of rotationally hindered C3-naphthylated indoles in moderate to good yields and high regioselectivity. This method can tolerate normal air conditions, and features the use of palladium/scandium cooperative catalysts without any ligand, facile double annulation involving various internal alkynes, and good functional group tolerance.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 7531-52-4, in my other articles. Safety of H-Pro-NH2.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI