Chemistry is an experimental science, name: (S)-Diphenyl(pyrrolidin-2-yl)methanol, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 112068-01-6, Name is (S)-Diphenyl(pyrrolidin-2-yl)methanol
Mukaiyama-Michael reactions with acrolein and methacrolein: A catalytic enantioselective synthesis of the C17-C28 fragment of pectenotoxins
Enantioselective iminium-catalyzed reactions with acrolein and methacrolein are rare. A catalytic enantioselective Mukaiyama-Michael reaction that readily accepts acrolein or methacrolein as substrates, affording the products in good yields and 91-97% ee, is presented. As an application of the methodology, an enantioselective route to the key C17-C28 segment of the pectenotoxin using the Mukaiyama-Michael reaction as the key step is described.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: (S)-Diphenyl(pyrrolidin-2-yl)methanol, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 112068-01-6, in my other articles.
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI