Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Computed Properties of C17H19NO, Which mentioned a new discovery about 112068-01-6
New chiral compounds, (S)-N-acylpyrrolidinylmethanols (1b-f and 1h), were synthesized and chiral methyltitanium diisopropoxides (2a-h) were prepared from 1a-h.Enantioselective carbon-carbon bond formation between aromatic carbaldehydes and 2a-h was achieved in yields of 90-97 percent and 10.5-54.1 percent ee.The chiral auxiliaries (1a-h) were recovered in almost quantitative yields without any loss of optical purity.Keywords: (S)-N-acylpyrrolidinylmethanol; carbon-carbon bond formation; enantioselective reaction; methyltitanium diisopropoxide; (R)-1-(1-naphthyl)ethanol; (R)-1-phenylethanol; (S)-prolinol
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 112068-01-6, help many people in the next few years.Computed Properties of C17H19NO
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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI