A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, SDS of cas: 18531-99-2, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 18531-99-2, Name is (S)-[1,1′-Binaphthalene]-2,2′-diol, molecular formula is C20H14O2. In a Article, authors is Hagemann, Bernhard，once mentioned of 18531-99-2
17 monodentate phosphepine ligands with a 4,5-dihydro-3H-dinaphtho[2,1- c;1?,2?-e]phosphepine structural motif have been synthesized and tested in the asymmetric hydrogenation of various beta-keto esters. By variation of the substituents of the aryl group on the phosphorus atom a fine tuning of the selectivity of the catalytic system is possible. Quantitative yield and enantioselectivities up to 95% ee have been achieved for the hydrogenation of methyl acetoacetate (7a), methyl 3-oxovalerate (7b) and ethyl 4-phenyl-3-oxo-propionate (7d) using 4-(4-methoxyphenyl)-4,5-dihydro-3H- dinaphtho-[2,1-c;1?,2?-e]phosphepine (4g) as ligand. Best enantioselectivities were obtained at comparably high temperatures (100-120C), which had the advantage of increased reaction rates.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 18531-99-2, help many people in the next few years.SDS of cas: 18531-99-2
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI