4730-54-5, 1,4,7-Triazacyclononane is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Di-tert-butyl dicarbonate (Boc2O, 5.1 g, 23.2 mmol) in anhydrous trichloromethane (30 mL) was added dropwise to a stirred solution of TACN (2.0 g, 15.5 mmol) and triethylamine (4.7 mL, 3.1 g, 31.0 mmol) in anhydrous trichloromethane (100 mL). The resulting reaction mixture was stirred for 24 h at room temperature. Excess triethylamine was removed by washing the reaction mixture with water (3 ¡Á 50 mL) and brine (2 ¡Á 50 mL). The organic layer was collected and dried over anhydrous magnesium sulfate and then filtered. The solvent was evaporated under reduced pressure to give the crude products which were purified by chromatography over silica (EtOAc(EA)/Petroleum ether(PE), 1 : 1, v/v) as colorless oil 2Boc-TACN (1) (Rf = 0.5, EA).
4730-54-5, The synthetic route of 4730-54-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Wang, Bing; Yi, Wen-Jing; Zhang, Ji; Zhang, Qin-Fang; Xun, Miao-Miao; Yu, Xiao-Qi; Bioorganic and Medicinal Chemistry Letters; vol. 24; 7; (2014); p. 1771 – 1775;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI