In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Nucleobase oxidation of DNA by (terpyridyl)chromium(III) derivatives, published in 2004-05-03, which mentions a compound: 89972-77-0, mainly applied to oxidation DNA terpyridyl chromium derivative, Recommanded Product: 4-(p-Tolyl)-2,2:6,2-terpyridine.
The Cr(III) complexes [Cr(ttpy)2](ClO4)3 (I) and [Cr(Brphtpy)2](ClO4)3 (II), containing the terpyridyl derivatives ttpy and Brphtpy [ttpy = p-tolylterpyridine; Brphtpy = (p-bromophenyl)terpyridine] were synthesized and characterized by ESI-MS, electronic spectroscopy, and cyclic voltammetry. Absorption titration and thermal denaturation studies reveal that both complexes are moderate binders of calf thymus DNA (CT DNA), while viscosity measurements show that they bind with partial intercalation. Binding of the 2 Cr complexes to DNA and mononucleotides dGMP, dAMP, dCMP, and dTMP decreases the emission intensity of II. However, the emission intensity of I is quenched only by DNA and the nucleotides dGMP and dAMP. Excited state potentials of both I and II have been estimated to be 1.65 and 1.85 V vs. NHE. These results demonstrate that II is a stronger photooxidant than I and other (diimine)chromium complexes, and that it can oxidize nucleobases. The photonuclease activity of I and II was confirmed by gel electrophoresis.
After consulting a lot of data, we found that this compound(89972-77-0)Recommanded Product: 4-(p-Tolyl)-2,2:6,2-terpyridine can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI