The author of 《Enantioselective Synthesis of 2-Oxindole Spirofused Lactones and Lactams by Heck/Carbonylative Cyclization Sequences: Method Development and Applications》 were Hu, Huaanzi; Teng, Fan; Liu, Jian; Hu, Weiming; Luo, Shuang; Zhu, Qiang. And the article was published in Angewandte Chemie, International Edition in 2019. Quality Control of Tris(dibenzylideneacetone)dipalladium(0) The author mentioned the following in the article:
An efficient one-pot assembly of all-carbon spiro-oxindole compounds from non-oxindole-based materials has been developed through a palladium-catalyzed asym. Heck/carbonylative lactonization and lactamization sequence [e.g., I → II (92%, 91% ee)]. Diversified spirooxindole γ-and δ-lactones/lactams were accessed in high yields with good to excellent enantioselectivities (up to 99 % ee) under mild reaction conditions. The natural product coixspirolactam A was conveniently synthesized by applying the current methodol., and thus its absolute configuration was elucidated for the first time. Asym. synthesis of an effective CRTH2 receptor antagonist has also been demonstrated utilizing this method in the key step. In the part of experimental materials, we found many familiar compounds, such as Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3Quality Control of Tris(dibenzylideneacetone)dipalladium(0))
Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3) is the most widely used PdO precursor complex in synthesis and catalysis, in particular as a catalyst for various coupling reactions. Quality Control of Tris(dibenzylideneacetone)dipalladium(0) It is used as a catalyst precursor for palladium-catalyzed carbon-nitrogen bond formation, conversion of aryl chlorides, triflates and nonaflates to nitroaromatics.
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI