In 2019,Nature Communications included an article by Zalesskiy, Sergey S.; Kitson, Philip J.; Frei, Przemyslaw; Bubliauskas, Andrius; Cronin, Leroy. Synthetic Route of C51H42O3Pd2. The article was titled 《3D designed and printed chemical generators for on demand reagent synthesis》. The information in the text is summarized as follows:
Modern science has developed well-defined and versatile sets of chems. to perform many specific tasks, yet the diversity of these reagents is so large that it can be impractical for any one lab to stock everything they might need. At the same time, issues of stability or limited supply mean these chems. can be very expensive to purchase from specialist retailers. Here, we address this problem by developing a cartridge-oriented approach to reactionware-based chem. generators which can easily and reliably produce specific reagents from low-cost precursors, requiring minimal expertise and time to operate, potentially in low infrastructure environments. We developed these chem. generators for four specific targets; transition metal catalyst precursor tris(dibenzylideneacetone)dipalladium(0) [Pd2(dba)3], oxidising agent Dess-Martin periodinane (DMP), protein photolinking reagent succinimidyl 4,4′-azipentanoate (NHS-diazirine), and the polyoxometalate cluster {P8W48}. The cartridge synthesis of these materials provides high-quality target compounds in good yields which are suitable for subsequent utilization. The results came from multiple reactions, including the reaction of Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3Synthetic Route of C51H42O3Pd2)
Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3) is the most widely used PdO precursor complex in synthesis and catalysis, in particular as a catalyst for various coupling reactions. Synthetic Route of C51H42O3Pd2 It also used for palladium-catalyzed one-pot synthesis of tricyclic indolines, in the Suzuki-Miyaura coupling of 2-pyridyl nucleophiles and cross-coupling of aryl halides with aryl boronic acids.
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI