In 2019,Synthetic Communications included an article by Ohtsuka, Yuhki; Hagiwara, Hideki; Miyazaki, Takanori; Yamakawa, Tetsu. Recommanded Product: Tris(dibenzylideneacetone)dipalladium(0). The article was titled 《Palladium-Catalysed Amination of Hindered Aryl Halides with 9H-Carbazole》. The information in the text is summarized as follows:
Palladium-catalyzed Buchwald-Hartwig amination of ortho-substituted hindered aryl bromides or chlorides RX (R = 2-tolyl, 1,1′-biphenyl-2-yl, naphth-1-yl, naphthalen-1-ylphenyl; X = Br, Cl) with 9H-carbazole has been investigated. In the amination of 1-bromo- or chloronaphthalene with 9H-carbazole, the combined use of Pd2(dba)3 as a Pd precursor, Buchwald ligands with two tert-Bu groups and LiOtBu or lithium hexamethyldisilazide as a base led to satisfactory yields. N,N’-Bis[2,6-bis(diphenylmethyl)-4-methoxyphenyl]imidazol-2-ylidene (IPr*OMe), which is a bulky N-heterocyclic carbene ligand, showed similar activity as Buchwald ligands with two tert-Bu groups. In contrast, only IPr*OMe provided satisfactory yields in the amination of 2-bromo-1,1′-biphenyl with 9H-carbazole. The amination of 2-bromo- or chlorotoluene and 1-(2-bromo- or chlorophenyl)naphthalene with 9H-carbazole proceeded smoothly when the IPr*OMe ligand was used. The results came from multiple reactions, including the reaction of Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3Recommanded Product: Tris(dibenzylideneacetone)dipalladium(0))
Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3) is the most widely used PdO precursor complex in synthesis and catalysis, in particular as a catalyst for various coupling reactions. Recommanded Product: Tris(dibenzylideneacetone)dipalladium(0) It also used for palladium-catalyzed one-pot synthesis of tricyclic indolines, in the Suzuki-Miyaura coupling of 2-pyridyl nucleophiles and cross-coupling of aryl halides with aryl boronic acids.
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI