With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.448-61-3,2,4,6-Triphenylpyrylium tetrafluoroborate,as a common compound, the synthetic route is as follows.
General procedure: To a suspension of the corresponding amine (2.0 mmol) and 2,4,6-triphenylpyrylium tetrafluoroborate (2.0 mmol) in EtOH (20 mL) in a round bottle flask was added Et3N (2.0 mmol). The mixture turned deep-brown while the educts dissolved and was stirred for 30 min at rt followed by the addition of AcOH (4.0 mmol) and heating under reflux conditions for additional 2 h. The product precipitated during the reaction. The product was dissolved directly in the flask with little acetone at the reflux temperature after the reaction was finished (no further precipitate occurred). After cooling down to rt the product crystallized as a yellow solid, which was filtered off, washed with cold EtOH and pentane and dried in vacuo., 448-61-3
448-61-3 2,4,6-Triphenylpyrylium tetrafluoroborate 9930615, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Article; Menzel, Roberto; Kupfer, Stephan; Mede, Ralf; Goerls, Helmar; Gonzalez, Leticia; Beckert, Rainer; Tetrahedron; vol. 69; 5; (2013); p. 1489 – 1498;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI