Bertrand, Helene; Monchaud, David; De Cian, Anne; Guillot, Regis; Mergny, Jean-Louis; Teulade-Fichou, Marie-Paule published the article 《The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes》. Keywords: terpyridine derivative ligand preparation transition metal complex; DNA binding terpyridine derivative ligand transition metal complex.They researched the compound: 4-(p-Tolyl)-2,2:6,2-terpyridine( cas:89972-77-0 ).Recommanded Product: 4-(p-Tolyl)-2,2:6,2-terpyridine. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:89972-77-0) here.
A family of terpyridine metallo-organic complexes (of Cu, Pt, Ru and Zn) was designed and its recognition properties of G-quadruplex-DNA studied. The series combines easy synthetic access and good affinity-selectivity ratio for quadruplex-DNA. The authors’ study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.
As far as I know, this compound(89972-77-0)Recommanded Product: 4-(p-Tolyl)-2,2:6,2-terpyridine can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI