Analyzing the synthesis route of 10534-59-5

10534-59-5, As the paragraph descriping shows that 10534-59-5 is playing an increasingly important role.

10534-59-5, Tetrabutylammonium acetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Step 3: Preparation of tetrabutylammonium salt of 4-{3-[(25,5/f)-6-(sulfooxy)-7-oxo-l,6-diaza- bicyclo[3.2.1]octane-2-carbonyl]-ureido}-piperidine-l-carboxylic acid tert-butyl ester: To a stirred solution of 4-{ 3-[(2S,5R)-(6-hydroxy-7-oxo-l,6-diaza-bicyclo[3.2.1]octane-2-carbonyl)-ureido] }- piperidine-l-carboxylic acid tert-butyl ester (0.41 g, 0.0009 mol) in dimethylformamide (4.1 ml), at 10C, was added dimethylformamide sulfur trioxide complex (0.183 g, 0.0019 mol) in one portion. The reaction mass was stirred at the same temperature for about 30 minutes and then allowed to warm to room temperature. After 1 hour, to the resulting reaction mixture was added slowly a solution of tetrabutylammonium acetate (0.359 g, 0.0019 mol) in dichloromethane (2 ml) under stirring. After 1 hour, the solvent from the reaction mixture was evaporated under reduced pressure to yield an oily residue. The oily mass was co-evaporated with xylene (2x10ml) to obtain a thick mass. This mass was partitioned between dichloromethane (10 ml) and water (10 ml). The combined organic extracts were washed with water (3xl0ml) and dried over anhydrous sodium sulphate.The solvent was evaporated under reduced pressure and the resulting oily mass was triturated with ether (3×10 ml), each time the ether layer was decanted and finally the residue was concentrated under reduced pressure to obtain 0.260 g of the titled product as white foam in 35% yield.Analysis:Mass: 490.4 (M-l) as free acid; for Molecular Weight: 732.9, Molecular Formula: C34H64N6O9S .

10534-59-5, As the paragraph descriping shows that 10534-59-5 is playing an increasingly important role.

Reference£º
Patent; WOCKHARDT LIMITED; TADIPARTHI, Ravikumar; PATIL, Vijaykumar Jagdishwar; KALE, Amol; SHAIKH, Mohammad Usman; PATEL, Mahesh Vithalbhai; (65 pag.)WO2016/116788; (2016); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI