1435-55-8, Hydroquinidine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
From dihydroquinidine To a 0 C. solution of 1.22g dihydroquinidine (0.0037 mol) in 30mL of CH2 Cl2 was added 0.78mL of Et3 N (0.0056 mol; 1.5 eq), followed by 0.71mL of p-chlorobenzoyl chloride (0.005 mol; 2 eq) in 1mL CH2 Cl2 After stirring 30 minutes at 0 C. and 1 hour at room temperature, the reaction was quenched by the addition of 10% Na2 CO3 (20mL). After separation, the aqueous layer was extracted with three 10mL portions of CH2 Cl2. The combined organic layers were dried over Na2 S04 and the solvent removed under vacuum. The crude product was purified as described above. Dihydroquinidine p-chlorobenzoate (1) was obtained in 91% yield (1.5g) as a white foam.
1435-55-8, 1435-55-8 Hydroquinidine 16401293, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Patent; Massachusetts Institute of Technology; US4965364; (1990); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI