With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
General procedure: To a solution of 2-phenyl-3-hydroxy-4(1H)-quinolinone (237 mg, 1 mmol) in ethanol (50 mL), the corresponding bidentate N-donor ligand (L) (1 mmol) dispersed in EtOH (5 mL) was added while stirring. To this mixture, a solution of Cu(BF4)2¡¤H2O (237 mg, 1 mmol) in H2O (5 mL) was slowly added while stirring. The reaction mixture was stirred at room temperature for a few hours, and subsequently left to stand for several days at room temperature. The obtained solid product was filtered off, washed with a small amount of cold water and ethanol, and dried in the air at 40 C., 1662-01-7
The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Buchtik, Roman; Travnicek, Zdenek; Vanco, Jan; Journal of Inorganic Biochemistry; vol. 116; (2012); p. 163 – 171;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI