With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
In a 1000 ml three-vial bottle,Under nitrogen protection,Add 200 ml of anhydrous ethanol,200 ml of toluene,21 g (0.1 mol) of 1,10-phenanthroline-5,6-diamine, 10.6 g (0.1 mol) of benzaldehyde,1 ml glacial acetic acid,After the addition, the temperature was gradually raised to reflux for 6 hours.After cooling, the reaction solution was concentrated to dryness under reduced pressure.The resulting solid was recrystallized from a mixed solvent of chloroform and ethanol.27.1 g of 2-phenyl-1H-imidazo[4,5-f][1,10]phenanthroline was obtained.Yield 91.55percent.
168646-54-6, 168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Patent; Li Xianwei; (29 pag.)CN107973811; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI