4045-44-7, As the paragraph descriping shows that 4045-44-7 is playing an increasingly important role.
4045-44-7, 1,2,3,4,5-Pentamethylcyclopenta-1,3-diene is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
All glassware was dried in a 10000C oven, assembled and kept under a nitrogen purge throughout reaction. All solvents used were anhydrous. To a 100 mL, three-neck round bottom flask equipped with a reflux condenser, teflon stir bar, gas inlet, glass stopper and septum was added cobalt octacarbonyl (6.Og; 17.5 mmol) . The septum was replaced and assembled reaction flask purged an additional 5 minutes. Dichloromethane (50 mL) was then canulated into reaction flask and solution stirred for 5 minutes. To the reaction solution was added 1,2,3,4,5- pentamethylcyclopentadiene (3.1g; 22.7 mmol) and 1,3- cyclohexadiene ((2.5 mL; 26.2 mmol) . Septum was replaced with glass stopper and reaction mixture was stirred and brought to a gentle reflux which was maintained for one (1) hour. The reaction was cooled just until reflux stopped followed by a second addition of 1, 2, 3, 4, 5-pentamethylcyclopentadiene (2.4 g; 17.6 mmol) . Reflux was then continued for another two (2) hours. The reaction was then cooled and stirred overnight at room temperature.The condenser was and replaced with a gas inlet and the volatile material removed under reduced pressure maintaining a flask temperature of 15 – 20C. The dark red crude material (7.89g) was then transferred into a glovebox. The crude material was dissolved in hexanes (30 mL) and loaded into a column of alumina (Brockman I – neutral) previously rinsed with hexanes (200 mL) . The title compound was then eluted as an orange-brown band with hexanes (80OmL) . The solvent was removed under reduced pressure yielding deep red crystals of the title compound (6.09g; 70% based on Co2 (CO) 8) .The synthesis can be represented as follows: Co2(CO)8 + 2C5Me5H + C6H8 ? 2 [Co (omega5-C5Me5) (CO)2] + C6Hi0 + 4C0Analytical Characterization: 1H NMR spectrum was taken using a Bruker Avance 300 Spectrometer 1H NMR (C6D6) delta 1.6 (s, 5 CH3)
4045-44-7, As the paragraph descriping shows that 4045-44-7 is playing an increasingly important role.
Reference£º
Patent; PRAXAIR TECHNOLOGY, INC.; WO2008/124599; (2008); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI