Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Safety of N1,N2-Diphenylethane-1,2-diamine, Which mentioned a new discovery about 150-61-8
The reaction of N,N’-di-tert-butylethylenediamine with glyoxal in water gives initially trans-2,3-dihydroxy-1,4-di-tert-butylpiperazine, 6f, which rearranges thermally to 1,3-di-tert-butyl-2-imidazolidinecarboxaldehyde, 8f, and then to 1,4-di-tert-butyl-2-ketopiperazine, 5f.The reaction of N,N’-diisopropylethylenediamine with glyoxal in water produces 1,4-diisoproyl-2-ketopiperazine, 5e, as the only isolable product.The reaction of a series of N,N’-dialkyl-substituted ethylenediamines with glyoxal in ethanol at low temperature has been found to give a series of cis-trans-cis-1,4,6,9-tetraalkyl-1,4,6,9-tetraaza-5,10-dioxaperhydroanthracenes, 9b,c,e, as minor products.The crystal structure of 9e was determined confirming the stereochemistry of the ring junctures.N,N’-Diphenylethylenediamine reacts with glyoxal to give 1,3-diphenyl-2-imidazolidinecarboxaldehyde, 8d. 8d shows no tendency to rearrange to 5d.A modified reaction scheme or the reaction of N,N’-disubstituted ethylenediamines with glyoxal is presented which accounts for the formation of these new types of products.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Product Details of 150-61-8, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 150-61-8
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI