23364-44-5. Name is (1S,2R)-2-Amino-1,2-diphenylethanol, belongs to catalyst-ligand compound, is a common compound. In an article, authors is Azizoglu, Murat, once mentioned the new application about 23364-44-5.
beta-Hydroxyamide-based ligands and their use in the enantioselective borane reduction of prochiral ketones
Hydroxyamide-based ligands have occupied a considerable place in asymmetric synthesis. Here we report the synthesis of seven beta-hydroxyamide-based ligands from the reaction of 2-hydroxynicotinic acid with chiral amino alcohols and test their effect on the enantioselective reduction of aromatic prochiral ketones with borane in tetrahydofuran (THF). They produce the corresponding secondary alcohols with up to 76% enantiomeric excess (ee) and good to excellent yields (86-99%). Chirality 26:21-26, 2013. 2013 Wiley Periodicals, Inc.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 23364-44-5
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI