Application of 14162-94-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.14162-94-8, Name is 4-Chloro-2,2′-bipyridine, molecular formula is C10H7ClN2. In a Article，once mentioned of 14162-94-8
A novel fluorine-18 method employing rhenium(i) mediation is described herein. The method was found to afford moderate to high radiochemical yields of labelled rhenium(i) complexes. Subsequent thermal dissociation of the complexes enabled the radiosynthesis of fluorine-18 labelled pyridine bidentate structures which could not be radiofluorinated hitherto. This rhenium(i) complexation-dissociation strategy was further applied to the radiosynthesis of [18F]CABS13, an Alzheimer’s disease imaging agent, alongside other 2,2?-bipyridine, 1,10-phenanthroline and 8-hydroxyquinoline labelled radiotracers. Computational modelling of the reaction mechanism suggests that the efficiency of rhenium(i) activation may be attributed to both an electron withdrawal effect by the metal center and the formation of an acyl fluoride intermediate which anchors the fluoride subsequent to nucleophilic addition.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 14162-94-8 is helpful to your research. Application of 14162-94-8
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI