Electric Literature of 7531-52-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 7531-52-4, Name is H-Pro-NH2, SMILES is O=C(N)[C@H]1NCCC1, belongs to catalyst-ligand compound. In a article, author is Kim, Hyunho, introduce new discover of the category.
Indol-2-ylidene (IdY): Ambiphilic N-Heterocyclic Carbene Derived from Indole
The synthesis of ambiphilic N-heterocyclic carbene ligand, indol-2-ylidene (IdY, A), is described. A series of indolenium precursors (2 a-f) were prepared on a gram scale in good yields. Trapping experiments with elemental selenium, [RhCl(cod)](2) and CuCl provided the expected carbene adducts. Further computational and spectroscopic studies supported the ambiphilicity of IdY, which lies between cyclic (alkyl)(amino)carbenes (CAAC-5) and cyclic (amino)(aryl)carbene (CAArC). The copper complexes (6) show high percent buried volume (% V-bur = 58.1) and allow for carboboration of terminal alkynes within 30 minutes in a demonstration of synthetic utility with good yields and high regioselectivity.
Electric Literature of 7531-52-4, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 7531-52-4 is helpful to your research.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI