Reference of 1119-97-7, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1119-97-7, Name is MitMAB, molecular formula is C17H38BrN. In a Article£¬once mentioned of 1119-97-7
U-shaped conformation of alkyl chains bound to a synthetic receptor cucurbit[8]uril
The behavior of a series of alkanes bound to the molecular host cucurbit[8]uril (CB[8]) has been systematically studied by 2D 1H NMR spectroscopy and isothermal titration calorimetry (ITC). CB[8] and alkyltrimethylammonium (CmTA+, (CH3) 3N+CmH2m+1, m=6-16) form 1:1 host-guest complexes with a high binding constant (K?106m -1). The shortest hexyl chain of C6TA+ can be fully encapsulated in an extended conformation inside the CB[8] cavity, which is driven by both enthalpy and entropy. However, for the longer aliphatic chains, C8-C16, the long alkyl tails take a U-shaped conformation inside the cavity, and their complexation is dominantly or almost exclusively enthalpy-driven, owing to the increased van der Waals contact between the folded aliphatic chain and the inner wall of the host cavity. As the chain length increases from C8 to C16, the ammonium head group of the guests moves away from the portal of CB[8] while the long aliphatic tails maintain the U-shaped conformation inside the cavity. The complexation of C mTA+ with CB[8] follows the enthalpy-entropy compensation rule commonly observed in molecular recognition systems. For example, among the guest molecules, C12TA+ shows the highest enthalpic gain (most favorable), owing to the large van der Waals contact between the guest and the host cavity, and at the same time the most unfavorable entropic contribution, owing to the severe conformational restriction of the U-shaped alkyl chain inside the host. The enthalpy-entropy compensation plot for the complexation suggests large conformational changes of the long alkyl chains and extensive dehydration associated with the inclusion complex formation. This guest is bent on fitting in: Alkyltrimethylammonium and cucurbit[8]uril (CB[8]) form 1:1 host-guest complexes with a high binding constant (K?10 6m-1). A short hexyl chain can be fully encapsulated in an extended conformation inside the CB[8] cavity, whilst for longer aliphatic chains, from octyl to cetyl, the alkyl tails take on a U-shaped conformation inside the cavity, which follows the enthalpy-entropy compensation rule commonly observed in molecular recognition systems. Copyright
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Reference of 1119-97-7, you can also check out more blogs about1119-97-7
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI