Mamba, Feziwe Bathabile; Ndlovu, Thando; Mbizana, Siyasanga; Khan, Wesaal; Gule, Nonjabulo Prudence published an article about the compound: Basic copper carbonate( cas:12069-69-1,SMILESS:O[Cu]OC(O[Cu]O)=O ).Name: Basic copper carbonate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:12069-69-1) through the article.
Appropriate wound care is pivotal in preventing wound and postsurgery infections, which remain a serious clin. problem. In this study, we report the successful fabrication of antimicrobial and biodegradable materials for possible use in the medical field. Amino functionalized polycaprolactone (PCL [Poly(CL-co-ACL)]) was synthesized via ring opening polymerization This polymer was then functionalized via the pendant amine to induce antimicrobial efficacy. This was done through the grafting of poly(lysine) onto the amine as well as the quaternization of the amine using alkyl halides. The chem. structures of the synthesized monomers and polymers were confirmed using NMR (1H NMR and 13C NMR) spectroscopy and attenuated total reflection-Fourier transform IR spectroscopy. The mol. weights of the polymers were determined using gel permeation chromatog. Nanofibre scaffolds were produced from the polymers using the electrospinning technique and these were characterized though SEM. The antimicrobial efficacy of the fabricated materials was tested against the Gram-pos. (Staphylococcus aureus ATCC 25923) and Gram-neg. (Pseudomonas aeruginosa ATCC 27853) bacteria using the disk diffusion and shake flask methods. The polymers demonstrated excellent antimicrobial efficacy. The fibers were exceptionally biodegradable which opens a lot of applications in the biomedical space.
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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI