Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 72-19-5, Name is H-Thr-OH, molecular formula is C4H9NO3, belongs to catalyst-ligand compound, is a common compound. In a patnet, author is Srivastava, Abhishek, once mentioned the new application about 72-19-5, Safety of H-Thr-OH.
Quantitative Estimation of D-Penicillamine in Pure and Pharmaceutical Samples Using Inhibitory Kinetic Spectrophotometric Method
Sulfur is the key element in a large number of drugs and bioactive molecules. Organo-sulfur compounds inhibit the catalytic efficiency of Hg2+ by forming a stable complex with it. The Hg2+ catalyzed exchange rate of cyanide with pyrazine from [Ru(CN)(6)](4-) will be reduced by the addition of the sulfur-containing drug, D-penicillamine (D-PCN). This inhibitory property of D-PCN can be employed for its micro-level kinetic determination. Optimum reaction condition viz. Temperature = 45.0 +/- 0.1 degrees C, I = 0.1 M (KCl), [Hg+2] = 1.5 x 10(-4) M, [pyrazine] = 7.5 x 10(-4) M, pH = 4.0 +/- 0.02, and [Ru(CN)(6)(4-)] = 5.25 x 10(-5) M were utilized to investigate the kinetic measurements at 370 nm (lambda(max) of [Ru(CN)(5) Pz](3-) complex). To acknowledge the inhibition induced by D-PCN on Hg2+ catalyzed substitution of cyanide with pyrazine from [Ru(CN)(6)](4-), a modified mechanistic scheme has been proposed. D-PCN can be quantitatively determined up to 1.0 x 10(-6) M level by the proposed analytical method. The methodology can be economically and effectively employed for the quantitative determination of D-PCN in different samples. This methodology can also be convincingly adopted for the quick determination of D-PCN in the pharmaceutical samples with good accuracy and reproducibility. The addition of common excipients in pharmaceuticals even up to 1000 times with [D-PCN] does not interfere significantly in the estimation of D-PCN.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 72-19-5. The above is the message from the blog manager. Safety of H-Thr-OH.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI