In an article, author is Kang, Houng, once mentioned the application of 7531-52-4, Category: catalyst-ligand, Name is H-Pro-NH2, molecular formula is C5H10N2O, molecular weight is 114.15, MDL number is MFCD00005253, category is catalyst-ligand. Now introduce a scientific discovery about this category.
Nickel-Catalyzed Vinylidene Insertions into O-H Bonds
A (pybox)Ni catalyst (where pybox = pyridine-bis(oxazoline)) promotes the reductive cyclization of beta-hydroxy 1,1-dichloroalkenes to form 2,3-dihydrofurans. The substrates for this reaction are conveniently prepared by an aldol addition, followed by one-carbon homologation. Chiral substrates are accessible in highly enantioenriched form, allowing for the synthesis of stereochemically complex 2,3,4-trisubstituted products. Mechanistic studies support a vinylidene O-H insertion rather than a C-O cross-coupling pathway.
If you are interested in 7531-52-4, you can contact me at any time and look forward to more communication. Category: catalyst-ligand.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI