《Arylenebis(tertiary phosphines) and -(phosphinic acids)》 was published in Journal of Organic Chemistry in 1967. These research results belong to Baldwin, Roger A.; Cheng, Ming T.. Computed Properties of C18H14BrOP The article mentions the following:
BuLi was utilized to prepare arylenemono- or -dilithiums from which monosubstituted tertiary phosphines and phosphinic acids as well as bis(tertiary phosphines) and bis(phosphinic acids) have been obtained. Monobromo-substituted tertiary phosphines were similarly converted to bis(tertiary phosphines). The use of tetrahydrofuran as the reaction solvent at low temperatures (below -65°) generally provided the best reaction conditions. The experimental part of the paper was very detailed, including the reaction process of (3-Bromophenyl)diphenylphosphine oxide(cas: 10212-04-1Computed Properties of C18H14BrOP)
(3-Bromophenyl)diphenylphosphine oxide(cas: 10212-04-1) belongs to mono-phosphine Ligands.Phosphine ligands are the most significant class of ligands for cross-coupling because of the alterability of their electronic and steric properties. Ligands play a key role in stabilizing and activating the central metal atom and are used in reactions, such as transition metal catalyzed cross-coupling.Computed Properties of C18H14BrOP
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI