Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 57709-61-2, molcular formula is C14H8N2O4, introducing its new discovery. Quality Control of: 1,10-Phenanthroline-2,9-dicarboxylic acid
An Improved Route for the Synthesis of Guanine Quadruplex Ligand Phen-DC3
The recognition of noncanonical DNA and RNA architectures such as guanine quadruplexes by small molecule ligands has become a promising strategy for anticancer and antiviral applications in recent years, leading to an exponential increase in the number of quadruplex ligands reported in the literature. There is consequently a need for ‘benchmark’ compounds which can be used as controls to facilitate comparisons between novel and previously reported ligands. One candidate for this role is Phen-DC3, which binds with high affinity and selectivity to guanine quadruplexes. To encourage its use in this role, an alternate synthetic route for the production of Phen-DC3 that may be more appropriate for implementation on a large scale is reported. This pathway eliminates the need for several hazardous reagents and increases the overall synthetic yield from 21% to a maximum of 43%.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Quality Control of: 1,10-Phenanthroline-2,9-dicarboxylic acid, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 57709-61-2
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Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI