With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.119-91-5,2,2′-Biquinoline,as a common compound, the synthetic route is as follows.
To a solution of cis-[Pt(p-MeC6H4)2(SMe2)2] (0.040 g, 0.078 mmol) in acetone (6 mL) was added a solution of biquinoline (0.020 g, 0.078 mmol) in acetone (6 mL) and the mixture was stirred for 2 h. The solvent was evaporated and a red precipitate product separated and washed twice with n-hexane. Then, the precipitate was dried in vacuum. (Yield: 84%), red, m.p: 160 C (decomp.), Anal. Calc. for [C32H26N2Pt] (1): (M.W: 633.654), C, 60.66; H, 4.14; N, 4.42%. Found: C, 60.09; H, 4.25; N, 4.17%; IR (KBr, y/cm1): (C]C) and (C]N) 1594sh, 1508sh, 1481s, 1431w, (CeH) 815sh, 800s, 746w, (MCl) 509w. 1H NMR (400 MHz, DMSO-d6, d/ppm): 2.17 (6H, s, C6H5CH3), 6.66 (4H, d, 3J(HoHm) 7.60 Hz, 7.23 (d, 4H, 3J(HmHo) 8.00 Hz, 7.29 (3J(PtHo) 17.21 Hz), 8.88 (d, 2H, 3J(H3H4) 8.40 Hz, H3 and H30 of biq), 8.63 (d, 2H, 3J(H4H3) 8.80 Hz, H4 and H40 of biq), 8.33 (dd, 2H, 3J(H8H7) 8.80 Hz, 3J(H8H6) 8.80 Hz, H8 and H80 of biq), 7.86 (d, 2H, 3J(H5H6) 8.00 Hz, H5 and H50 of biq), 7.51 (t, 2H, 3J(H6H5), 3J(H6H7) 16.0 Hz, H6 and H60 of biq). 7.61 (t, 2H, 3J(H7H6), 3J(H7H8) 16.81 Hz, H7 and H70 of biq)., 119-91-5
The synthetic route of 119-91-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Shafaatian, Bita; Heidari, Bahareh; Journal of Organometallic Chemistry; vol. 780; (2015); p. 34 – 42;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI