With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4730-54-5,1,4,7-Triazacyclononane,as a common compound, the synthetic route is as follows.
0.75 g (5.6 mmol) of 1,4,7-triazacyclononane was completely dissolved in 50 mL of ethanol, followed by 2.8 mL(20.2 mmol) triethylamine and 2.71 g (19.6 mmol) bromoacetamide, and the mixture was heated under reflux and stirred for 6 hours, then naturally cooled to room temperature, suction filtered, and the white solid obtained was vacuum dried at 35 C. to obtain the ligand represented by Formula I.
As the paragraph descriping shows that 4730-54-5 is playing an increasingly important role.
Reference£º
Patent; Shaanxi Normal University; Liu Jing; Quan Jingmiao; Lei Hairui; Yan Junlin; (8 pag.)CN104892533; (2017); B;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI