5350-41-4,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5350-41-4,N,N,N-Trimethyl-1-phenylmethanaminium bromide,as a common compound, the synthetic route is as follows.
General procedure: To a 50mL Schlenk tube containing benzylic ammonium iodide (0.5mmol), arylboronic acid (2.0mmol), K3PO4 (2.25mmol), castalyst (5molpercent) and PPh3 (20molpercent) were added and the tube was purged with N2 for 3 times. Then 1,4-dioxane (2.0mL), subsequently, was introduced to the tube. The resulted mixture was allowed to stir for 24h at 80¡ãC under atmosphere of N2. After the completion of the reaction, the resulting mixture was filtered through a Celite pad and concentrated under the vacuum and directly purified by flash chromatography to give the desired product.
As the paragraph descriping shows that 5350-41-4 is playing an increasingly important role.
Reference£º
Article; Liu, Xi-Yu; Zhu, Hai-Bo; Shen, Ya-Jing; Jiang, Jian; Tu, Tao; Chinese Chemical Letters; vol. 28; 2; (2017); p. 350 – 353;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI