Chemistry is an experimental science, name: (1S,2S)-(-)-1,2-Diphenylethylenediamine, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 29841-69-8, Name is (1S,2S)-(-)-1,2-Diphenylethylenediamine
The catalytic asymmetric ring opening of meso-epoxides with aromatic amines was achieved using a new proline-based N,N?-dioxide-indium tris(triflate) complex in high yields (up to 99%) with excellent enantioselectivities (up to 99% ee) under mild conditions. The coordination ability of N,N?-dioxide 1c was investigated by X-ray and NMR analysis. A plausible seven-coordinate transition state model was proposed. The chiral N,N?-dioxides surveyed were synthesized from proline through only three conventional steps. The procedure could be run on a gram-scale without any loss of enantioselectivity. This protocol provides a highly practical and useful tool for the bulky preparation of optically pure beta-amino alcohols.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: (1S,2S)-(-)-1,2-Diphenylethylenediamine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 29841-69-8, in my other articles.
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI