Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， name: 2,6-Naphthalenedicarboxylic Acid, Which mentioned a new discovery about 1141-38-4
A series of HIV-1 integrase inhibitors containing a novel metal binding motif consisting of the 8-hydroxy-1,6-naphthyridine core and either an oxadiazole or triazole has been identified. The design of the key structural components was based on a two-metal coordination pharmacophore. This report presents initial structure-activity data that shows the new chelation architecture delivers potent inhibition in both enzymatic and antiviral assays.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 1141-38-4, help many people in the next few years.name: 2,6-Naphthalenedicarboxylic Acid
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI