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The synthesis of three types of mesoporous materials is reported: pure mesoporous silica (MCM-41), a nanocomposite of mesoporous silica with hydroxyapatite (MCM-41-HA) and mesoporous silica/gold nanorods nanocomposite (MCM-41-GNRs). The mesoporous materials were characterized by X-ray diffraction, N2 adsorption isotherms, FTIR spectroscopy, transmission electron microscopy, and scanning electron microscopy. The samples were loaded with coumarin thiourea derivatives (I-IV) having functional groups of varying sizes and the in vitro release assays were monitored, and the release behavior was investigated as a function of soaking time in simulated body fluid. Two release stages were obtained in MCM-41, MCM-41-HA and MCM-41-GNRs loaded samples with the early release stages accounting for about 30% of loaded derivatives. These early release stages are characterized by Higuchi rate constant values nearly twice the values associated with the second release stages. The influence of substituent size on the release rate constants was explained in terms of sorption sites and hydrogen bonding with silanol groups on silicates. The release of coumarin derivatives loaded on MCM-41, MCM-41-HA and MCM-41-GNRs occurs over remarkably long time of the order of about 260 h with faster release rates in loaded MCM-41 and MCM-41-GNRs samples compared with MCM-41-HA ones. The role of hyperthermia effect in enhancing release rates was investigated by subjecting loaded MCM-41-GNRs to near infrared (NIR) radiation at 800 nm. This would be of significance in targeted drug release using hyperthermia effect. Unlike hydroxyl apatite, loading MCM-41 with gold nanorods does not affect the release kinetics. Only when these samples are irradiated with NIR photons, does the release occur with enhanced rates. This property could be valuable in selected targeting of drugs.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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This invention relates to cleaning and disinfection of apples and pears through the feed of aqueous blends of select disinfectant chemicals and select cleaning chemicals to provide simultaneous cleaning and sanitation on produce and food processing surfaces.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Displacement chromatography is a powerful technique for protein purification, but the availability of high-efficacy displacers has greatly limited its applications. In this work, a displacer-immobilized ligand docking scheme was developed for the prediction of displacer efficacy and displacer screening for displacement chromatography of proteins. The structure of immobilized ligand was established by coupling a certain number of ligands to the 3D structure of agarose. A number of known cation, anion and hydrophobic displacers were docked to their respective immobilized ligands to verify the effectiveness of the scheme, and the Spearman ranking correlation coefficients of all cases were over 0.5. The scheme was then used to screen displacers for hydrophobic charge induction chromatography from over 1800 commercially available compounds. Column displacement experiments of several representative compounds showed that the identified displacers were efficacious in the displacement of single component and binary mixtures. It is expected that the combination of the docking scheme with the existing techniques for displacer discovery/design would greatly facilitate the discovery of high-affinity displacers for protein purification.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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This article describes a unique combination of inkjet printing of functional materials with an intricate self-assembly process. Gold-silver nanowire (NW) mesh films were produced by a sequential deposition process, in which small metal seed nanoparticle film was deposited at desired areas by inkjet printing, followed by coating with a thin film of NW growth solution. Two different types of NW growth solutions were used: the first, based on benzylhexadecyldimethylammonium chloride, exhibited a bulk solution growth mode and was thus suitable for coverage of large uniform areas. The second type was based on hexadecyltrimethylammonium bromide, which induced NW growth confined to the substrate-solution interface and thus enabled patterning of small transparent electrode features, which have the same dimensions as the deposited seed droplets. A selective silver plating bath was used to thicken the ultrathin NWs, stabilize them, and reduce the sheet resistance, resulting in films with sheet resistance in the range of 20-300 Omega/sq, 86-95% light transmission, and a relatively low haze. This simple patterning method of the NW film works at ambient conditions on many different types of substrates and has the potential to replace the conventional photolithography used for indium tin oxide patterning for applications such as touch sensors and flexible/stretchable electronics.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Nitrogen containing surfactants (e.g. amines, amides, imidazolines, and quaternary ammonium salts) have been commonly used as active corrosion inhibitors in commercial corrosion inhibitor (CI) packages for many years to control corrosion of carbon steel pipelines in the oil and gas industry. However, in the literature, not many systematic studies have been done to compare the partitioning behavior and corrosion performance of nitrogen-based CIs with different functional groups, and their inhibition mechanisms are currently not fully understood. In this study, nitrogen-based model CI compounds with different functional groups and sulfur containing synergist molecules were selected for mechanistic study. The oil-water partitioning behavior and corrosion performance of these model compounds were investigated and correlated to their chemical structures in a variety of sweet corrosion environments. The desorption behavior of the model CIs were studied and correlated to their film persistency and performance. Mechanistic understanding of the structure-behavior-performance relationships of the model CIs and synergist molecules will not only significantly accelerate CI selection for new field development but also enhance the confidence and reliability of the existing CI programs.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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The invention relates to a process for preparing triaryl organoborates proceeding from alkyl or cycloalkyl boronates in the presence of an n-valent cation 1/n Kn+ and to the use of these substances as co-initiator in photopolymer formulations.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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Colloidal aphrons are multi-layered stable bubbles (CGAs) or droplets (CLAs), surrounded by a thin surfactant film. The small size of the aphrons creates a system with a high interfacial area which can be pumped like water without collapsing. The high stability of colloidal aphrons due to a thin soapy shell surrounding the core, and high interfacial area make them of interest in many processes such as mineral processing, protein recovery, drilling fluids, separation of organic dyes from waste water, predispersed solvent extraction of dilute streams, clarification and purification of suspensions, soil remediation, material synthesis and immobilization of enzymes. This article aims to provide a comprehensive database in generation, characterization and applications of colloidal gas and liquid aphrons from more than 140 published works so far. The article also reports scale up, industrial applications, technical limitation regarding aphrons application and important future research scopes.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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The invention discloses a method for the preparation of a benzalkonium chloride. The preparation method comprises the following steps, (1) in the organic solvent, in the 30 – 70 C, the fatty alkyl dimethyl tertiary amine with benzyl chloride to salt forming reaction, get aliphatic alkyl dimethyl benzyl ammonium chloride can be; the fatty alkyl is dodecyl, tetradecyl or cetyl; wherein the organic solvent is methanol, ethanol, n-propanol, isopropanol, acetone and acetonitrile in the one or more; (2) in the organic solvent, will contain two or three steps (1) prepared in the fatty alkyl dimethyl benzyl ammonium chloride mixture, crystallization, can be. Preparation method of the invention process is simple, high yield, can reach 90% or more; the relevant substance content is low, high purity, can be up to 99% or more, low water content, can realize the good shape of the appearance of the product, after treatment is simple effect, meet the requirements of Pharmacopoeia, is suitable for industrial production pharmaceutical the level benzene grips the chlorine ammonium. (by machine translation)

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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In this work, various types of antimicrobial and insect-resist agents were microencapsulated by several techniques to minimise their toxicity to humans. The microencapsulated antimicrobial and insect-resist agents were applied to wool fabrics by a pad-dry-bake method, and their performance was assessed in accordance with standard methods. The durability of the treatments to ageing and washing was evaluated. It was found that the antimicrobial and insect resist agents migrated to the outer surface of the capsules during ageing. Of the antimicrobial agents investigated, poly(N,N-dimethyl-2-hydroxypropylammonium) chloride or Barquat PQ 2 encapsulated with polylactic acid showed the best overall antibacterial performance after 10 cycles of International Wool Secretariat (IWS) 7A washing and also after ageing. The clothianidin insecticide encapsulated with polylactic acid showed the best insect-resist performance according to Wools of New Zealand Test Method 25 at a level of 50 ppm, passing this test method even after 10 cycles of washing. The washed fabric showed 85% insect mortality and the mean wool mass loss was only 4.6 mg. The fabric handle properties were only slightly affected by the treatments. The developed methods may find application in industry as they are quite durable to washing.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

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In recent years, much effort has been made to produce gold (Au) nanorods of different sizes through the use of binary surfactant mixtures via a seed-mediated growth approach. However, how the ratio of two different surfactants influences the shape of the resulting Au nanoparticles remains to be elucidated. Here, we report the shape-controlled synthesis of Au nanoparticles using a binary surfactant mixture of CTAB (cetyltrimethylammonium bromide) and DDAB (didodecyldimethylammonium bromide) via a silver-assisted seed-mediated growth approach. Decreasing the CTAB/DDAB ratio results in a shape transition from Au nanorods to elongated tetrahexahedra and finally to Au bipyramids. The results showed significant improvement in the yield of Au bipyramidal type nanoparticles in different sizes (nm to mum) by using binary surfactant mixtures without any need for shape selection procedure. By varying the pH and concentration of ascorbic acid, we can control the shape and size of Au nanoparticles (i.e., truncated bipyramids, dogbones, and nanodumbbells) at fixed CTAB/DDAB ratios. A preliminary growth mechanism has been proposed based on the change in the mixed micelle soft-template induced by the increasing concentration of DDAB and reaction parameters (i.e., pH, concentration of ascorbic acid). These results constitute the advances in the understanding for synthesizing anisotropic Au nanoparticles of tunable optical properties via engineering the design of a soft-template. These anisotropic Au nanoparticles, especially, bipyramids of different morphologies and sizes are potential candidates for the enhancement of the optical response and developing label-free biosensing devices.

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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI