Category: 1671-87-0

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1671-87-0,3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine,as a common compound, the synthetic route is as follows.

A 5¡Á10-6 M solution of compound 4 in 1:1 ethanol:H20 and a 5¡Á10-6 M solution of compound 12 in ethanol were prepared separately. 1 mL of each solution was added to a 3-mL UV cuvette, and the absorbance was measured every five minutes at room temperature for 40 minutes. Tetrazine 4 has an absorption maximum at 292 nm, and the product 13 has an absorption maximum at 312 nm. Also, product 13 displays significant absorption at 340 nm (e=12000), whereas tetrazine 4 displays minimal absorption (e=3000) at 340 nm. With monitoring at 292, 312 and 340 nm, the reaction was considered to be completed in 40 min

1671-87-0, 1671-87-0 3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine 315109, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; University of Delaware; US2009/23916; (2009); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1671-87-0, 3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1671-87-0, A 10-3 M solution of compound 4 in 1:1 ethanol:H2O and a 10-2 M solution of compound 12 in ethanol were prepared separately. 50 muL of the 10-3 M solution of compound 4 and 50 muL of the 10-2 M solution of compound 12 were added to a glass vial containing 1 mL of 10% untreated rabbit reticulocyte lysate in H2O. The solution was stirred at room temperature for 1 hr. The solution was extracted with ether and CH2Cl2, dried over Na2SO4, filtered through celite, and concentrated in vacuo. The resulting residue was diluted with 100 muL of methanol and analyzed by ESI-MS and compound 13 was detected. The yield was 76% versus an internal standard.

The synthetic route of 1671-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; University of Delaware; US2009/23916; (2009); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI