Category: 168646-54-6

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

168646-54-6, 0.33 g of 4,4′-dinitrobenzil (1.0 mmol) and 0.21 g of 5,6-diamine-1,10-phenanthroline (1.0 mmol) were put into a 100 mL single-necked flask, 30 mL of glacial acetic acid was added, Stirring, reaction under nitrogen 2h. After the reaction was completed, the solvent was removed by rotary evaporation and spin-dried. An appropriate amount of dichloromethane was added and the mixture was stirred for 10 min. Filtration, rotary evaporation of the solvent. The resulting solid was recrystallized from absolute ethanol, suction filtered and dried in vacuo to give 0.352 g of pale yellow crystals, The yield is 78.6percent. The reaction is:

The synthetic route of 168646-54-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Jiangnan University; Zheng Changge; Xie Chen; Li Mingyue; (8 pag.)CN105884833; (2016); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

[Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to a DCMsolution (about 12 mL) of dap (10.7 mg, 98percent, 0.0500 mmol) andxantphos (59.0 mg, 98percent, 0.100 mmol) under a stream of dry argonby using Schlenk techniques at room temperature and a vacuumlinesystem, then orange-red solution was obtained quickly andstirred for 1 h at room temperature. The above process can alsobe carried out in air with the existence of oxygen. After filtrationthrough absorbent cotton, layering n-hexane onto the DCM solutionin air produced the product as bluish violet to black-blue blockcrystals in 76percent yield (63.0 mg). Anal. Calc. for C90H72Cl2Cu2N4O10P4(1b): C, 63.97; H, 4.30; N, 3.32. Found: C, 64.25; H, 4.35; N, 3.26percent.ESI-MS (m/z): 1589.25 {[Cu2(l-pdi)(xantphos)2]ClO4}+ (calcd1589.27); 849.1963 [Cu(pdi)(xantphos)]+ (calcd 849.1968);745.153 [Cu2(l-pdi)(xantphos)2]2+ (calcd 745.159); 641.1222[Cu(xantphos)]+ (calcd 641.1224). 1H NMR (400 MHz, DMSO-d6,delta, ppm): 13.190 (s, 2H, CNH), 9.030 (d, 2H, J = 8.0 Hz), 8.452 (d,2H, J = 4.8 Hz), 7.888 (dd, 2H, J = 8.0 Hz, J0 = 1.2 and 0.8 Hz),7.846?7.814 (m, 4H), 7.340?7.149 (m, 36H), 6.983?6.938 (m, 8H),6.729?6.694 (m, 2H), 6.650?6.615 (m, 2H), 1.732 (s, 6H, CH3),1.653 (s, 6H, CH3). 31P{1H} NMR (400 MHz, DMSO-d6, delta, ppm):5.980, 12.816. Characteristic IR spectrum (KBr, cm-1): 3258m(NH), 2961m (CH3), 2923w (CH3), 2858w (CH3); 1097s (ClO4).

168646-54-6, The synthetic route of 168646-54-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yao, Xi-Xi; Guo, Ya-Meng; Liu, Rong; Feng, Xiao-Yan; Li, Hao-Huai; Liu, Nian; Yang, Feng-Lei; Li, Xiu-Ling; Polyhedron; vol. 92; (2015); p. 84 – 92;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: [Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to a DCMsolution (about 12 mL) of dap (10.7 mg, 98percent, 0.0500 mmol) andxantphos (59.0 mg, 98percent, 0.100 mmol) under a stream of dry argonby using Schlenk techniques at room temperature and a vacuumlinesystem, then orange-red solution was obtained quickly andstirred for 1 h at room temperature. The above process can alsobe carried out in air with the existence of oxygen. After filtrationthrough absorbent cotton, layering n-hexane onto the DCM solutionin air produced the product as bluish violet to black-blue blockcrystals in 76percent yield (63.0 mg)., 168646-54-6

As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Reference£º
Article; Yao, Xi-Xi; Guo, Ya-Meng; Liu, Rong; Feng, Xiao-Yan; Li, Hao-Huai; Liu, Nian; Yang, Feng-Lei; Li, Xiu-Ling; Polyhedron; vol. 92; (2015); p. 84 – 92;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The respective diketo compound and 1, 10-phenanthroline-5, 6-diamine were dissolved in methanol followed by catalytic amountof acetic acid and the mixture was refluxed for 5-6 h. The mixturewas cooled to room temperature and the solid separated wasfiltered, washed with small amount of cold methanol followed byhexane and dried well to get red colored product.

168646-54-6, The synthetic route of 168646-54-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kothavale, Shantaram; Sekar, Nagaiyan; Dyes and Pigments; vol. 136; (2017); p. 31 – 45;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 1,10-phenanthroline-5,6-diamine (1 mmol), 2,3-dihydroxybenzaldehyde (1 mmol) and EtOH (10 mL) was heated at 70-80 ¡ãC for 24 h. The reaction mixture was cooled to room temperature, dried and concentrated in vacuo. Yield: 89percent. Anal. Calcd for C19H12N4O2: C, 69.51; H, 3.68; N, 17.06. Found: C, 69.39; H, 3.72; N, 17.10. ESI-MS: 328 ([Mr+H]+). 1H NMR (300 MHz, CD3OD-d6): delta 8.91 (d, J = 9.0 Hz, 2H), 8.52 (d, J = 9.0 Hz, 2H), 8.03 (t, J = 8.1 Hz, 2H), 7.22 (d, J = 7.2 Hz, 2H,), 7.12 (d, J = 6.9 Hz, 2H,), 5.79 (s, 1H). 13C NMR (300 MHz, CD3OD-d6): delta 165.19, 160.92, 154.56, 150.56, 143.36, 141.25, 138.11, 134.75, 133.58, 133.24, 131.56, 127.85, 125.56, 124.36, 123.78, 122.56, 121.45, 120.21.

168646-54-6, As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Reference£º
Article; Zhang, Pingyu; Huang, Wenxiu; Wang, Yi; Li, Haihang; Liang, Chunmei; He, Chuanxin; Wang, Haitao; Zhang, Qianling; Inorganica Chimica Acta; vol. 469; (2018); p. 593 – 599;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

In a 1000 ml three-vial bottle,Under nitrogen protection,Add 200 ml of anhydrous ethanol,200 ml of toluene,21 g (0.1 mol) of 1,10-phenanthroline-5,6-diamine, 10.6 g (0.1 mol) of benzaldehyde,1 ml glacial acetic acid,After the addition, the temperature was gradually raised to reflux for 6 hours.After cooling, the reaction solution was concentrated to dryness under reduced pressure.The resulting solid was recrystallized from a mixed solvent of chloroform and ethanol.27.1 g of 2-phenyl-1H-imidazo[4,5-f][1,10]phenanthroline was obtained.Yield 91.55percent.

168646-54-6, 168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Li Xianwei; (29 pag.)CN107973811; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

4,7-phenanthroline-5,6-dione (1 eq, 0.096 mol) and 1,10-phenanthroline-5,6-diamine (1.1 eq, 0.106 mol) after mixing, these were added to 300 mL of acetic acid and dissolved, followed by stirring under reflux for 12 hours. Thereafter, the reaction solution was put into distilled water, and the obtained solid was filtered, washed several times with distilled water,the residue was purified by rum chromatography to obtain an A-4 compound (yield: 43percent)., 168646-54-6

The synthetic route of 168646-54-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; LG Display Co., Ltd.; Hyeong Min-seok; Choi Seul-gi; Lee Tae-yang; (40 pag.)KR2019/42882; (2019); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under nitrogen protection,A solution of 5-bromo-1-phenylindole-2,3-dione (Intermediate a) (30.2 g, 0.1 mol) and 1,10-phenanthroline-5,6-diamine (Intermediate b ) (21.0 g, 0.1 mol) was added to 200 mL of absolute ethanol.The reaction was allowed to warm to 70-75 ¡ã C for 24 hours.Reaction is completed, cooled to room temperature after the direct suction filter,The filter cake was rinsed with absolute ethanol and the crude product was crystallized from dichloroethane / absolute ethanol to give a yellow solid,That is the intermediate c, the yield of 70percent.

168646-54-6, As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Reference£º
Patent; Wanrun Pharmaceutical Co., Ltd.; Zhang, Xueheng; Ju, Chengliang; Shi, Yu; Yang, Teng; Chi, Pengli; Yang, Hao; (17 pag.)CN106366083; (2017); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

5mmol of Phen-NH2, 5.5mmol of indoline-2,3-dione and 0.1mmol of 4-methylbenzenesulfonic acid were added into 25mL of ethanol and heated to reflux overnight. After cooling, the solution was poured into 300mL of cold water. The crude product was collected and recrystalized in ethanol to yield IPP as gray powder. 1H NMR (300Hz, CDCl3, 25¡ãC): delta 10.13 (d, 1H, J=8.5Hz), 9.24 (d,1H, J=2.5Hz), 9.17 (d, 1H, J=2.0Hz), 9.09 (d, 1H, J=5.5Hz), 8.55 (d, 1H, J=5.5Hz), 7.60?7.64 (m, 2H), 7.55 (d, 1H, J=8.5Hz), 7.34 (m, 2H). Anal. Calcd for C20H11N5: C, 74.76; H, 3.45; N, 21.79. Found: C, 74.67, H, 3.60; N, 21.68., 168646-54-6

As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Reference£º
Article; Li, Xiaogang; Zhang, Dong; Li, Jing; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 127; (2014); p. 1 – 9;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.168646-54-6,5,6-Diamino-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

In a 100mL single-necked flask was added 0. 33g4,4′-dinitrobenzil (l.Ommol) and 0. 21g 5,6-diamine-1,10-phenanthroline (1.0 mmol)Add 30mL glacial acetic acid,Stirring, reaction under nitrogen 2h. After the reaction,Rotate the solvent, spin-dry after adding the appropriate amount of dichloromethane stirring lmin.Filtration, rotary evaporation of the solvent. The resulting solid is anhydrousEthanol recrystallized, suction filtered and dried in vacuo to give pale yellow crystals 0. 352g, a yield of 78.6percent.

168646-54-6, As the paragraph descriping shows that 168646-54-6 is playing an increasingly important role.

Reference£º
Patent; Jiangnan University; Zheng Changge; Xie Chen; Li Mingyue; (7 pag.)CN105884835; (2016); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI