Category: 32780-06-6

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about A ring-expansion route to analogs of dideoxyhydantocidin, the main research direction is dideoxy hydantocidin spirocyclic nucleoside preparation; dihydrofuranyllithium addition azetidinedione; hydroxy lactam acid catalyzed rearrangement.Reference of (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one.

The acid-catalyzed rearrangement of hydroxy β-lactam, formed by addition of the enantiopure dihydrofuranyllithium to N-benzyl-2,3-azetidinedione, has been investigated as a potential route to spirocyclic nucleosides.

There are many compounds similar to this compound(32780-06-6)Reference of (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

COA of Formula: C5H8O3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about Chirospecific synthesis of (S)-(+)- and (R)-(-)-5-amino-4-hydroxypentanoic acid from L- and D-glutamic acid via (S)-(+)- and (R)-(-)-5-hydroxy-2-oxopiperidine. Author is Herdeis, C..

(S)-H2NCH2CH(OH)CH2CH2CO2H [(S)-I] was prepared stereospecifically from L-glutamic acid in 6 steps. Thus, L-glutamic acid was converted to lactone II (R = CO2H), which was reduced by H3B.S(Me)2 to give II (R = CH2OH), which was O-mesylated and then treated with NaN3 to give II (R = CH2N3). The latter was hydrogenated over Pd/C to give piperidine III, which was cleaved by aqueous Ba(OH)2 to give (S)-I. (R)-I was prepared analogously from D-glutamic acid.

There are many compounds similar to this compound(32780-06-6)COA of Formula: C5H8O3. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about Two approaches to the enantioselective synthesis of (4R)-(-)-4-hydroxymethyl-4-thiobutyro-1,4-lactone. Author is Zunszain, Patricia A.; Varela, Oscar.

Enantiomerically pure (4R)-4-hydroxymethyl-4-thiobutyro-1,4-lactone [(5R)-dihydro-5-(hydroxymethyl)-2(3H)-thiophenone (I)] and derivatives were synthesized by two enantiospecific sequences employing D-ribono-1,4-lactone (II) and L-glutamic acid (III) as chiral templates. The key step in the first approach was the SmI2-promoted 2,3-deoxygenation of a 4-thio-L-lyxono-1,4-lactone derivative, prepared from II. The other strategy, which starts from III, involves the (5S)-dihydro-5-(p-tolylsulfonyloxymethyl)-2-(3H)-furanone (IV) as chiral precursor. This was converted into a 4,5-thiirane derivative via the corresponding 4,5-epoxide. Regioselective opening of the thiirane ring by acetate followed by O-deacetylation gave I (40% overall yield from IV).

There are many compounds similar to this compound(32780-06-6)Name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

COA of Formula: C5H8O3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about Chirospecific synthesis of (S)-(+)- and (R)-(-)-5-amino-4-hydroxypentanoic acid from L- and D-glutamic acid via (S)-(+)- and (R)-(-)-5-hydroxy-2-oxopiperidine. Author is Herdeis, C..

(S)-H2NCH2CH(OH)CH2CH2CO2H [(S)-I] was prepared stereospecifically from L-glutamic acid in 6 steps. Thus, L-glutamic acid was converted to lactone II (R = CO2H), which was reduced by H3B.S(Me)2 to give II (R = CH2OH), which was O-mesylated and then treated with NaN3 to give II (R = CH2N3). The latter was hydrogenated over Pd/C to give piperidine III, which was cleaved by aqueous Ba(OH)2 to give (S)-I. (R)-I was prepared analogously from D-glutamic acid.

There are many compounds similar to this compound(32780-06-6)COA of Formula: C5H8O3. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about A ring-expansion route to analogs of dideoxyhydantocidin, the main research direction is dideoxy hydantocidin spirocyclic nucleoside preparation; dihydrofuranyllithium addition azetidinedione; hydroxy lactam acid catalyzed rearrangement.Reference of (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one.

The acid-catalyzed rearrangement of hydroxy β-lactam, formed by addition of the enantiopure dihydrofuranyllithium to N-benzyl-2,3-azetidinedione, has been investigated as a potential route to spirocyclic nucleosides.

There are many compounds similar to this compound(32780-06-6)Reference of (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Formula: C5H8O3. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about Facile, highly stereoselective synthesis of 2′,3′-dideoxy- and 2′,3′-didehydro-2′,3′-dideoxy nucleosides via a furanoid glycal intermediate. Author is Kim, Choung Un; Misco, Peter F..

Regiospecific and highly stereoselective electrophilic addition reactions to the furanoid glycal I were used as key steps in the synthesis of 2′,3′-dideoxyadenosine (II) and 2′,3′-didehydro-3′-deoxythymidine (III) antiviral nucleosides.

I hope my short article helps more people learn about this compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Formula: C5H8O3. Apart from the compound(32780-06-6), you can read my other articles to know other related compounds.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 32780-06-6, is researched, SMILESS is O=C1O[C@H](CO)CC1, Molecular C5H8O3Journal, Heterocycles called A facile entry to bicyclic systems from L-glutamic acid, Author is Frieman, Bryan A.; Bock, Charles W.; Bhat, Krishna L., the main research direction is pyrrole fused pyrrolidinone furanone nonracemic preparation; facile entry bicyclic system glutamic acid; cycloaddition TosMIC alpha beta unsaturated cyclic amide lactam; calculated mol structure intermediate product synthesis density functional theory.SDS of cas: 32780-06-6.

Nonracemic pyrrole-fused pyrrolidinone I (X = BocN; Boc = tert-butoxycarbonyl) and furanone I (X = O) were prepared in seven steps from L-glutamic acid. The key step in the preparation of I (X = BocN, O) was the construction of the pyrrole rings in a single step through cycloadditions of tosylmethyl isocyanide (TosMIC) with the nonracemic cyclic α,β-unsaturated lactam and lactone II (X = BocN, O). E.g., II (X = BocN) was prepared in six steps from L-glutamic acid by cyclocondensation in water followed by treatment with thionyl chloride in methanol to yield a nonracemic oxopyrrolidinylcarboxylate ester which was reduced to give a nonracemic oxopyrrolidinylmethanol. E.g., the nonracemic oxopyrrolidinylmethanol was silylated with tert-butyldimethylsilyl chloride and N-protected with Boc anhydride; the protected oxopyrrolidinylmethanol was deprotonated with LDA and selenylated with phenylselenyl chloride to give an intermediate which underwent elimination upon treatment with hydrogen peroxide in the presence of DMAP. E.g., addition of a solution of II (X = BocN) in DMSO/ether to a solution of TosMIC and sodium hydride in DMSO/ether and stirring for 2 h gave I (X = BocN) in 97% yield. The structures of reaction intermediates and final products were investigated using d. functional theory calculations

Here is just a brief introduction to this compound(32780-06-6)SDS of cas: 32780-06-6, more information about the compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one) is in the article, you can click the link below.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called New synthesis of D-ribose from L-glutamic acid, published in 1971, which mentions a compound: 32780-06-6, mainly applied to ribose synthesis glutamic acid; stereospecific synthesis ribose; non carbohydrate saccharide preparation, Product Details of 32780-06-6.

L-Glutamic acid gave on HNO2 deamination a lactone, which was esterified to I (R = CO2Et), a suitable precursor to the preparation of D-ribose (II) without optical resolution. The reduction of I with NaBH4 gave I (R = CH2OH), converted to the benzyl ether I (R = CH2OCH2Ph) (III). Heating III with Na and HCO2Et in Et2O gave Na salt (IV) which was converted in 3 steps to 5-O-benzyl-2,3-dideoxy-D-glycero-pentofuranose (V). Consecutive bromination, methylation, and dehydrobromination gave the unsaturated pentose (VI), which was first oxidized with KMnO4, then hydrogenated over Pd-C, treated with 0.1N H2SO4. The mixture of II and D-xylose was separated through the anilide of II.

Here is just a brief introduction to this compound(32780-06-6)Product Details of 32780-06-6, more information about the compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one) is in the article, you can click the link below.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about First asymmetric total synthesis of (+)-steganacin. Determination of absolute stereochemistry. Author is Tomioka, Kiyoshi; Ishiguro, Tsuneo; Koga, Kenji.

(+)-Steganacin (I) was synthesized stereospecifically in 12 steps using the γ-lactone II as a chiral synthon. The key steps of the reaction were the specific asym. 1,4-addition of the chiral butenolide with lithiated trimethoxybenzaldehyde dithioacetal and the regio- and stereoselective introduction of Ac onto (+)-stegane to give I. The sign of optical rotation of I was opposite to that of natural steganacin, the absolute stereochem. of which was thus determined unequivocally.

Here is just a brief introduction to this compound(32780-06-6)Name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, more information about the compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one) is in the article, you can click the link below.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about Stereochemical control of nature’s biosynthetic pathways: a general strategy for the synthesis of polypropionate-derived structural units from a single chiral progenitor, the main research direction is polypropionate synthon hydroxymethylfuranone; ionomycin fragment preparation.HPLC of Formula: 32780-06-6.

A general strategy, based on (S)-5-hydroxymethyl-5H-furan-2-one, that permits the stereocontrolled construction of acyclic chains containing vicinal and/or alternating alkyl and hydroxy substituents is presented. Several structural subunits of ionomycin were synthesized from this common chiral intermediate.

Here is just a brief introduction to this compound(32780-06-6)HPLC of Formula: 32780-06-6, more information about the compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one) is in the article, you can click the link below.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI