Category: 40000-20-2

40000-20-2, 5-Bromo-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,40000-20-2

Synthesis of Compound 57: The compound 57a (3.9 g, 15.0 mmol),Phenoxazine (2.9 g, 16 mmol),Tert-butylphosphine (0.35 g, 2 mmol),Palladium acetate (0.4 g, 1.8 mmol) and cesium carbonate (9.7 g, 30 mmol) were dissolved in toluene,Under a nitrogen atmosphere,The reaction was heated under reflux for 10 hours.The solvent was evaporated in vacuo,The remaining material was stirred with pentane,filter,Purification by silica gel column chromatography,To obtain solid compound 5, (3.7 g, 10.2 mmol),Yield 62percent.

The synthetic route of 40000-20-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Shanghai Tianma Organic Shine Display Co., Ltd.; Tianmawei Electronic Co., Ltd.; Wang Xiangcheng; Liu Ying; Ren Hongyang; He Wei; Liu Chen; (43 pag.)CN106831743; (2017); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.40000-20-2,5-Bromo-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

To a mixture of 18 (274 mg, 0.63 mmol), 15 (163 mg,0.63 mmol), Pd(PPh3)Cl2 (22 mg, 5 molpercent) and anhyd. K2CO3(261 mg, 1.89 mmol) was added dry DMSO (5 mL) and degassedfor 15 min. The mixture was then heated at 100 C for 24 h. Aftercooling, H2O (10 mL) was added to the reaction mixture and theprecipitate that had formed was collected and washed with H2O(20 mL), EtOH (20 mL), acetone (5 mL) and allowed to dry under vacuum to provide 6 as a tan-colored solid (240 mg, 70percent): mp220 C dec; 1H NMR (500 MHz,CDCl3) d 9.23 (m, 2H), 8.85 (s, 2H),8.75 (d, 2H, J = 4.01 Hz), 8.71 (d, 2H, J = 9.16 Hz), 8.32 (m, 2H),8.10 (d, 2H, J = 8.02 Hz), 7.91 (dt, 2H, J = 8.02, 1.72 Hz), 7.83 (s,1H), 7.69 (m, 3H), 7.63 (m, 1H), 7.38 (m, 2H); 13C NMR(125 MHz, DMSO-d6) d 156.4, 155.4, 150.8, 150.4, 149.9, 149.5,146.4, 145.7, 140.1, 138.1, 137.9, 137.6, 136.9, 134.6, 131.5,128.4, 127.8, 127.6, 127.5, 125.2, 124.3, 123.9, 121.5, 118.5.

40000-20-2, As the paragraph descriping shows that 40000-20-2 is playing an increasingly important role.

Reference£º
Article; Nair, Neelima V.; Zhou, Rongwei; Thummel, Randolph P.; Inorganica Chimica Acta; vol. 454; (2017); p. 27 – 39;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI