Category: 4199-88-6

Simple exploration of 4199-88-6

4199-88-6, The synthetic route of 4199-88-6 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4199-88-6,5-Nitro-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: A 0.5 mmol quantity of copper(II) nitrate trihydrate was treated with 1.0 mmol of phen (or nphen) in ethanol (20 ml) under stirring conditions for 0.5 h. The product was isolated, washed with ethanol and set aside for crystallization by slow evaporation at room temperature. Green crystals were crystallized from the solution after a week. The structure of [Cu(phen)2(H2O)](NO3)2 has been previously determined by Nakai and Deguchi [43], by Catalan et al. [44], by Szpakolski et al. [45], by Zhou [46] and by Boutebdja et al. [47]. Complex 1: Yield was 87%. Anal. Calcd. for C24 H18 Cu N8 O12 (673.99 g mol-1) (%): C, 43.18; H, 2.67; N,16.63. Found: C, 42.77; H, 2.69; N, 16.63.

4199-88-6, The synthetic route of 4199-88-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Inci, Duygu; Aydin, Rahmiye; Vatan, Oezguer; Yilmaz, Dilek; Genckal, Hasene Mutlu; Zorlu, Yunus; Cava?, Tolga; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 145; (2015); p. 313 – 324;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Brief introduction of 4199-88-6

As the paragraph descriping shows that 4199-88-6 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4199-88-6,5-Nitro-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

Complex 1 was prepared by a conventional synthetic method, in which a mixture ofdichloromethane and methanol (42 mL, 2:1) was added to a flask containing [Ir(Hppy)2Cl]2 (0.323 g,0.30 mmol) and NP (0.135 g, 0.60 mmol) [19]. The mixture was refluxed for 6 h under argon to givea red brown solution. After cooling, a bright red precipitate was obtained by dropwise additionof concentrated NH4PF6 aqueous solution with stirring at room temperature for 2 h. The crudeproduct was purified by column chromatography on alumina eluted with dichloromethane-acetone(1:3, v/v). The red band was collected, the solvent was evaporated under the reduced pressure, and abrown-yellow powder was obtained. Yield: 86%. Anal. Calc for C34H23F6N5O2PIr: C, 46.90; H, 2.66;N, 8.04%. Found: C, 46.81; H, 2.72; N, 8.12%. 1H NMR (500 MHz, DMSO-d6): 9.46 (s, 1H), 9.20 (d, 1H,J = 8.0 Hz), 9.12 (d, 1H, J = 7.5 Hz), 8.34 (dd, 2H, J = 5.5, J = 6.0 Hz), 8.26 (d, 2H, J = 8.0 Hz), 8.19-8.15(m, 2H), 7.95 (d, 2H, J = 8.0 Hz), 7.88 (t, 2H, J = 7.5 Hz), 7.52 (dd, 2H, J = 6.0, J = 6.0 Hz), 7.06 (t, 2H,J = 7.5 Hz), 7.01-6.94 (m, 5H), 6.26 (d, 2H, J = 7.5 Hz). 13C NMR (125 Hz, DMSO-d6): 166.70, 153.41,151.88, 149.56, 149.11, 147.87, 146.79, 144.96, 144.04, 140.80, 138.87, 135.24, 131.23, 130.33, 128.52, 128.34,127.45, 125.14, 123.97, 123.89, 122.60, 120.03. ESI-MS (CH3CN): m/z 725.9 ([M-PF6]+)., 4199-88-6

As the paragraph descriping shows that 4199-88-6 is playing an increasingly important role.

Reference£º
Article; Zhang, Li-Xia; Gu, Yi-Ying; Wang, Yang-Jie; Bai, Lan; Du, Fan; Zhang, Wen-Yao; He, Miao; Liu, Yun-Jun; Chen, Yan-Zhong; Molecules; vol. 24; 17; (2019);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Analyzing the synthesis route of 4199-88-6

As the paragraph descriping shows that 4199-88-6 is playing an increasingly important role.

4199-88-6, 5-Nitro-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Methanolic solution of CuCl22H2O (1.5 mmol) was added to methanolic solution of neutral bidentate ligand An(1.5 mmol), followed by the addition of a previously prepared methanolic solution of ciprofloxacin (1.5 mmol) in presence of CH3ONa (1.5 mmol). The reaction mixture was adjusted to ~6 pH. The resulting solution was refluxed for 1 h on a steam bath, followed by concentrating it to half of its volume. A fine amorphous product of green color obtained was washed with methanol followed by ether/hexane and was dried in vacuum desiccators. The proposed reaction for the synthesis of complexes 1-5 is shown in Scheme 1. All the synthesized complexes are soluble in DMSO. Elemental analysis data of synthesized complexes are kept in the Supplementary Material.

As the paragraph descriping shows that 4199-88-6 is playing an increasingly important role.

Reference£º
Article; Patel, Mohan N.; Gandhi, Deepen S.; Parmar, Pradhuman A.; Mehta, Jugal V.; Monatshefte fur Chemie; vol. 148; 5; (2017); p. 901 – 908;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Brief introduction of 4199-88-6

As the paragraph descriping shows that 4199-88-6 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4199-88-6,5-Nitro-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: [(eta3-C3H5)Mo(CO)2(NCMe)2Cl] (1; 200 mg; 0.64 mmol) was dissolved in CH2Cl2 (50 mL) and treated with 5-nitro-1,10-phenanthroline (145 mg, 0.64 mmol). The solution was stirred for 30 min at room temperature. After that, the solvent was vacuum evaporated. The crude product was washed with ether and recrystallized from the mixture CH2Cl2/ether and vacuum dried. Yield: 270 mg (93%, 0.60 mmol). Anal. Calcd for C17H12ClMoN3O4: C, 45.00; H, 2.67; N, 9.26. Found: C, 45.12; H, 2.70; N, 9.23. 1H NMR (d6-acetone, 400 MHz, 25 C, delta ppm): 9.45-9.40 (m, 2H,C12H7N2), 9.24 (d, J(1H,1H) = 8.2 Hz, 1H, C12H7N2), 9.16 (s, 1H, C12H7N2), 9.06 (d, J(1H,1H) = 8.2 Hz, 1H, C12H7N2), 8.19 (s, 1H, C12H7N2), 3.35 (m, 1H, C3H5), 3.29 (d, J(1H,1H) = 6.2 Hz, 2H, C3H5), 1.37 (d, J,(1H,1H) = 8.7 Hz, 2H, C3H5). FTIR (ATR, cm-1): 1930 vs [nua(CO)], 1842 vs [nus(CO)], 1540 [nus(NO)], 1535 [nua(NO)].

As the paragraph descriping shows that 4199-88-6 is playing an increasingly important role.

Reference£º
Article; Honzi?ek, Jan; Vinklarek, Jaromir; Pad?lkova, Zde?ka; ?ebestova, Lucie; Foltanova, Karolina; ?eza?ova, Martina; Journal of Organometallic Chemistry; vol. 716; (2012); p. 258 – 268;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI