Category: 4479-74-7

4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of 2,2?-bipyridine-6,6?-dicarboxylic acid (244 mg,1.0 mmol), Ru(DMSO)4Cl2 (484 mg, 1.0 mmol), and Et3N (0.8ml) in methanol (10 ml) was degassed with N2 and refluxed for 4 h. The solution changed from bright yellow to dark before the appearance of a brown precipitate. After cooling to room temperature, the precipitate was filtered and washed with methanol (10 ml ¡Á 3) and ether (10 ml ¡Á 3) to get a reddish-brown powder. The powder was mixed with an excess of 4,4?-bipyridine in methanol (20 ml) and heated to reflux for 2 h. The solvent was removed and the resulted residue was re-dissolved in dichloromethane, washed with water to remove triethylamine hydrochloride, and dried over MgSO4 under N2. After purification by column chromatography on silica gel with dichloromethane-methanol (20:1 to 1:1, V:V) as eluent, complex1 was obtained as a dark red solid. Yield: 229 mg (35%).

4479-74-7, The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Jiang, Yi; Li, Fei; Huang, Fang; Zhang, Biaobiao; Sun, Licheng; Cuihua Xuebao/Chinese Journal of Catalysis; vol. 34; 8; (2013); p. 1489 – 1495;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4479-74-7,2,2-Bipyridine-6,6-dicarboxylic Acid,as a common compound, the synthetic route is as follows.

General procedure: A mixture of 2,2?-bipyridine-6,6?-dicarboxylic acid (244 mg,1.0 mmol), Ru(DMSO)4Cl2 (484 mg, 1.0 mmol), and Et3N (0.8ml) in methanol (10 ml) was degassed with N2 and refluxed for 4 h. The solution changed from bright yellow to dark before the appearance of a brown precipitate. After cooling to room temperature, the precipitate was filtered and washed with methanol (10 ml ¡Á 3) and ether (10 ml ¡Á 3) to get a reddish-brown powder. The powder was mixed with an excess of 4,4?-bipyridine in methanol (20 ml) and heated to reflux for 2 h. The solvent was removed and the resulted residue was re-dissolved in dichloromethane, washed with water to remove triethylamine hydrochloride, and dried over MgSO4 under N2. After purification by column chromatography on silica gel with dichloromethane-methanol (20:1 to 1:1, V:V) as eluent, complex1 was obtained as a dark red solid. Yield: 229 mg (35%)., 4479-74-7

The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Jiang, Yi; Li, Fei; Huang, Fang; Zhang, Biaobiao; Sun, Licheng; Cuihua Xuebao/Chinese Journal of Catalysis; vol. 34; 8; (2013); p. 1489 – 1495;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

4479-74-7,4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of Tb(NO3)3¡¤6H2O (0.045 g, 0.10 mmol), H2bpdc (0.024 g, 0.10 mmol) in distilled water (10 mL) that adjusted the pH value to 2.5 with 0.5 mol L-1 NaOH aqueous solution. It was then sealed in a 25 mL Teflon reactor and heated at 160 C for 72 h, and then cooled to ambient temperature at a rate of ca.2 C h-1 to give colorless block crystals of 7, yield: 57% based on H2bpdc.

The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ren, Ya-Lan; Wang, Fei; Hu, Huai-Ming; Chang, Zhuguo; Yang, Meng-Lin; Xue, Ganglin; Inorganica Chimica Acta; vol. 434; (2015); p. 104 – 112;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4479-74-7,2,2-Bipyridine-6,6-dicarboxylic Acid,as a common compound, the synthetic route is as follows.

General procedure: A mixture of Tb(NO3)3¡¤6H2O (0.045 g, 0.10 mmol), H2bpdc (0.024 g, 0.10 mmol) in distilled water (10 mL) that adjusted the pH value to 2.5 with 0.5 mol L-1 NaOH aqueous solution. It was then sealed in a 25 mL Teflon reactor and heated at 160 C for 72 h, and then cooled to ambient temperature at a rate of ca.2 C h-1 to give colorless block crystals of 7, yield: 57% based on H2bpdc.

4479-74-7, As the paragraph descriping shows that 4479-74-7 is playing an increasingly important role.

Reference£º
Article; Ren, Ya-Lan; Wang, Fei; Hu, Huai-Ming; Chang, Zhuguo; Yang, Meng-Lin; Xue, Ganglin; Inorganica Chimica Acta; vol. 434; (2015); p. 104 – 112;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of Gd(NO3)3¡¤6H2O (0.023g, 0.05mmol), H2bpdc (0.024g, 0.10mmol) in distilled water (10mL) that adjusted the pH value to 5.5 with 0.5molL-1 NaOH aqueous solution was placed in a Teflon-lined stainless steel vessel (25mL), heated to 160C for 72h and then cooled to room temperature at a rate of 5C/h. The colorless crystalline product of 1 was obtained (yield: 35% based on H2bpdc)., 4479-74-7

The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ren, Ya-Lan; Wang, Fei; Hu, Huai-Ming; Chang, Zhuguo; Yang, Meng-Lin; Xue, Ganglin; Inorganica Chimica Acta; vol. 434; (2015); p. 104 – 112;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of Tb(NO3)3¡¤6H2O (0.045 g, 0.10 mmol), H2bpdc (0.024 g, 0.10 mmol) in distilled water (10 mL) that adjusted the pH value to 2.5 with 0.5 mol L-1 NaOH aqueous solution. It was then sealed in a 25 mL Teflon reactor and heated at 160 C for 72 h, and then cooled to ambient temperature at a rate of ca.2 C h-1 to give colorless block crystals of 7, yield: 57% based on H2bpdc.

4479-74-7, The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ren, Ya-Lan; Wang, Fei; Hu, Huai-Ming; Chang, Zhuguo; Yang, Meng-Lin; Xue, Ganglin; Inorganica Chimica Acta; vol. 434; (2015); p. 104 – 112;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

4479-74-7,4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of Ca(NO3)2¡¤4H2O (60.0mg, 0.25mmol), H2BD (10.0mg, 0.04mmol) and 2.0mL DMF was sealed in a 10mL pressure-resistant glass tube, which was then heated to 100C within 100min and kept at 100C for 1440min followed by slowly cooled to 30C within 200min. Colourless crystals were obtained and washed with DMF and then dried in the air (yield: 71%. Based on Calcium.). Elemental Anal. Calc. for 1 C18H22CaN4O6: C, 44.12; H, 4.90; N, 13.72. Found: C, 44.51; H, 4.73; N, 12.23%. IR (KBr): 3460 (s), 2931 (w), 1660 (s), 1611 (s), 1548 (s), 1386 (s), 1255 (w), 1099 (m), 851 (w) 788 (s) 688 (s) 576 (w)cm-1.

As the paragraph descriping shows that 4479-74-7 is playing an increasingly important role.

Reference£º
Article; Wang, Yutong; Fan, Weidong; Wang, Xia; Liu, Di; Huang, Zhaodi; Dai, Fangna; Gao, Jing; Polyhedron; vol. 155; (2018); p. 261 – 267;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

2,2′-Bipyridine-6,6′-dicarboxylic acid (0.37 g,1.5 mmol) in mixture of thionyl chloride (10 ml) and DMF (0.3 ml) wasrefluxed for 2.5 h. Then thionyl chloride was removed, the solid residuewas dissolved in absolute THF (15 ml) and the resulting solution was addedportionwise to a solution of tetraethyl [iminodi(methylene)]bis(phosphonate)(1 g, 3.15 mmol) and Et3N (1 ml) in absolute THF (10 ml). The mixturewas stirred at room temperature for 16 h. Then water (5 ml) was addedand the organic layer was separated, washed with water and dried overanhydrous Na2SO4. The solvent was evaporated to leave dark oil. Thendiethyl ether (5 ml) was added to the oil and the mixture was ground untilprecipitate formation. The precipitate was filtered off, washed with colddiethyl ether and dried in air to afford product 3 as white powder. Yield1 g (79%), mp 116-118C. 1H NMR (600 MHz, CDCl3) delta: 1.19 (t, 12H,CH2Me, 3J 7.0 Hz), 1.36 (t, 12H, CH2Me, 3J 7.0 Hz), 3.94-4.01 (m, 8H,CH2Me), 4.20-4.27 (m, 8H, CH2Me), 4.39 (d, 4H, 2CH2P, 2J 11.1 Hz),4.76 (d, 4H, 2CH2P, 2J 11.2 Hz), 7.85 (d, 2H, 3,3′-CH, 3J 7.5 Hz), 7.97(t, 2H, 4,4′-CH, 3J 7.7 Hz), 8.50 (d, 2H, 5,5′-CH, 3J 7.2 Hz). 13C NMR(100 MHz, CDCl3) delta: 16.2 (d, J 5.1 Hz), 16.3 (d, J 5.0 Hz), 41.3 (d,J 155.9 Hz), 44.5 (d, J 154.7 Hz), 62.2 (d, J 6.0 Hz), 62.6 (d, J 5.7 Hz),122.1, 125.4, 138.2, 152.5, 153.1, 167.5. 31P NMR (162 MHz, CDCl3) delta:2 1.64, 21.65. MS (MALDI-TOF), m/z: 881 [M+K]+. Found (%): C, 45.72;H, 6.51; N, 14.78. Calc. for C32H54N4O14P4 (%): C, 45.61; H, 6.46;N, 14.70., 4479-74-7

The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Farat, Oleg K.; Kharcheva, Anastasia V.; Ioutsi, Vitaliy A.; Borisova, Natalia E.; Reshetova, Marina D.; Patsaeva, Svetlana V.; Mendeleev Communications; vol. 29; 3; (2019); p. 282 – 284;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI