63-68-3, H-Met-OH is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
L-Methionine (0.5 g, 1 equivalent) was suspended in methanol (30 ml C=0.1M) in a 100 ml flask equipped with a magnetic stirrer and placed under nitrogen. Thionyl chloride (0.5 ml, 2 equivalents) was added to the solution dropwise at 0 C. then heated under reflux for 16 hours. The reaction mixture was then evaporated to yield a pale yellow solid. The solid was triturated with hot diethyl ether and the solution discarded to leave the title compound 2? a white solid which was further dried under vacuum. (0.65561 g, 98% yield). [0377] 1H NMR (D2O, 500 MHz) deltaH: 4.24 (1H, m, 3) 3.79 (3H, s, 1), 2.63 (2H, t, 5), 2.25 (1H, m, 4), 2.16 (1H, m, 4), 2.06 (1H, s, 6) [0378] 13C NMR (D2O, 125 MHz) deltac: 170.58 (2), 53.64 (1), 51.70 (3), 28.71 (4), 28.41 (5), 13.85 (6). [0379] IR (neat, vmax, cm-1): 2880.8/2676.2 (CH3, CH2, CH), 2016.2, 1742.2 (C?O, ester), 1483.6, 1443.5, 1227+1194.7+1149.8+1079.5 (C-O). [0380] HRMS m/z (+ESI): C6H14NO2S, mass found=164.074 (Error=0.071 ppm), 63-68-3
The synthetic route of 63-68-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; The University of Sussex; Viseux, Eddy Michel Elie; Gallop, Christopher; Bobin, Mariusz; US2014/39200; (2014); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI