Analyzing the synthesis route of 7173-51-5

As the paragraph descriping shows that 7173-51-5 is playing an increasingly important role.

7173-51-5, N-Decyl-N,N-dimethyldecan-1-aminium chloride is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

7173-51-5, Didecyldimethylammonium chloride (0.025 mol) was dissolved in 40 mL distilled water and the folic acid sodium salt (0.01 mol) was added. The solution was stirred at room temperature for 30 min. After separation of the phases, the organic phase was washed with distilled, cold water until chloride ions were no longer detected using AgNO3. The organic phase was separated and solvent was evaporated. The product (90% yield), didecyldimethylammonium N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoy]-L-glutamate, was dried at 50 C. under vacuum. Product is soluble in chloroform, acetone, DMSO. It lacks miscibility with water and hexane. 1H and 13C NMR (DMSO) were obtained. Thermogravimetric analysis: Tonset5%=153 C., and Tonset=201 C. 1H and 13C NMR (DMSO) were obtained.

As the paragraph descriping shows that 7173-51-5 is playing an increasingly important role.

Reference£º
Patent; Rogers, Robin D.; Daly, Daniel T.; Swatloski, Richard P.; Hough, Whitney L.; Davis, James Hilliard; Smiglak, Marcin; Pernak, Juliusz; Spear, Scott K.; US2007/93462; (2007); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Simple exploration of 7173-51-5

The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7173-51-5,N-Decyl-N,N-dimethyldecan-1-aminium chloride,as a common compound, the synthetic route is as follows.,7173-51-5

General procedure: In a round-bottom flask equipped with dropping funnel and reflux condenser 0.01 mol of (4-chloro-2-methylphenoxy)acetic acid, 40 mL of distilled water and 0.011 mol of 10% aqueous solution of NaOH was heated at 50 C until the mixture became a clear solution. Then a stoichiometric amount of quaternary ammonium chloride was added and the mixture was stirred for 30 min at room temperature. The product deposited as the bottom layer, which was separated. Then it was dissolved in 50 mL of chloroform. The organic phase was washed with distilled water until no chloride was present in water. After removal of chloroform the product was dried under reduced pressure at 60 C for 24 h.

The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Pernak, Juliusz; Syguda, Anna; Janiszewska, Dominika; Materna, Katarzyna; Praczyk, Tadeusz; Tetrahedron; vol. 67; 26; (2011); p. 4838 – 4844;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Brief introduction of 7173-51-5

As the paragraph descriping shows that 7173-51-5 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7173-51-5,N-Decyl-N,N-dimethyldecan-1-aminium chloride,as a common compound, the synthetic route is as follows.

7173-51-5, EXAMPLE 3 Preparation of 2,6-dinitro-3,4-dimethyl anisole A solution of 226 g 2,6-dinitro-3,4-xylenol, 93.7%. (1 mole) in two liters 1,2-dichloroethane was placed in a three liter reaction flask. Sodium carbonate 128 g (1.2 moles) and 0.81 g Didecyldimethyl-ammonium chloride (DDAC) were added to the above solution and afterwards 151.3 (1.2 moles) of dimethylsulfate were introduced during 15 minutes at the ambient temperature. The reaction mixture was heated with stirring to reflux during two hours. Water (400 ml) was added and heating was continued for another hour. This mixture was cooled to 25 C. and allowed to separate in two phases. The lower organic phase was separated, washed with water to neutral. The solvent was next recovered by distillation and the remaining oily produce solidified by cooling. A product (225.8 g) of 94%. 2,6-dinitro-3,4-dimethylanisole was obtained at a 93.9% of the theoretical yield based on 2,6-dinitro-3,4-xylenol consumed.

As the paragraph descriping shows that 7173-51-5 is playing an increasingly important role.

Reference£º
Patent; Agan Chemical Manufacturers Ltd.; US5475148; (1995); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Some tips on 7173-51-5

The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.

7173-51-5, N-Decyl-N,N-dimethyldecan-1-aminium chloride is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,7173-51-5

Equimolar amounts of mandelic acid, or (R)-(-)-mandelic acid or (S)-(+)-mandelic acid or L-proline and potassium hydroxide (scale 0.1 mol) were dissolved in distilled water (100 mL). After clarity of solution equimolar amount of quaternary ammonium chloride in distilled water (80 mL) was added. The mixture was heated at 60 C for 5 h. The water was removed under reduced pressure (70 C, 30¡Á102 Pa). Anhydrous methanol was added and the mixture was allowed to stand overnight at room temperature. The crystalline potassium chloride was removed by filtration and methanol by distillation. The obtained residue was dried overnight in vacuum at 80 C.

The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Cybulski, Jacek; Wi?niewska, Anna; Kulig-Adamiak, Anna; Da?browski, Zbigniew; Praczyk, Tadeusz; Michalczyk, Alicja; Walkiewicz, Filip; Materna, Katarzyna; Pernak, Juliusz; Tetrahedron Letters; vol. 52; 12; (2011); p. 1325 – 1328;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Simple exploration of 7173-51-5

The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7173-51-5,N-Decyl-N,N-dimethyldecan-1-aminium chloride,as a common compound, the synthetic route is as follows.,7173-51-5

In a round-bottom flask, equipped with a magnetic stirrer, heating bath, dropping funnel, and a reflux condenser, a suspension of 0.02 mol of 3,6-dichloro-2- methoxybenzoic acid in 30 mL of distilled water, was prepared. Then 0.02 mol of 10% aqueous solution of NaOH was added to the suspension. The reaction was conducted at 50C until the all acid reacted and a homogeneous reaction mixture was obtained. Then a stoichiometric amount of didecyldimethylammonium chloride was added in a 1 to 1 (50%: 50%) water and isopropanol mixture. The product precipitated from the reaction mixture in the form of a lower liquid layer. After 24 hours, the product was isolated by separating the phases. The organic phase was washed with distilled water from the unreacted substrate and the NaCl. In the final stage the product was dried for 24 hours at 50C under reduced pressure. The yield is 90%. 1H NMR (CDC13) delta ppm = 0.88 (t, J= 6.7 Hz, 6H), 1.25 (m, 28H), 1.61 (q, J = 6.8 Hz, 4H), 3.34 (s, 6H), 3.39 (t, J= 6.3 Hz, 4H), 3.95 (s, 3H), 6.99 (d, J= 8.5 Hz, 1H), 7.08 (d, J= 8.5 Hz, 1H); 13C NMR delta ppm = 14.0; 22.5; 26.1; 29.1; 29.25; 29.27; 31.7; 50.9; 61.5; 63.1; 125.3; 125.9; 127.0; 127.8; 140.2; 151.7; 167.9. Elemental analysis CHN CsoHssOsNCb: calculated C 65.90; H 9.79; N 2.56; observed: C 65.62; H 9.65; N 2.33. DSC: T glass -47C, mp 86C, T = 178C; 1 onset 232C

The synthetic route of 7173-51-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA; PERNAK, Juliusz; SHAMSHINA, Julia; TADEUSZ, Praczyk; SYGUDA, Anna; JANISZEWSKA, Dominika; SMIGLAK, Marcin; GURAU, Gabriela; DALY, Daniel, T.; ROGERS, Robin, D.; WO2012/6313; (2012); A2;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

Downstream synthetic route of 7173-51-5

7173-51-5 N-Decyl-N,N-dimethyldecan-1-aminium chloride 23558, acatalyst-ligand compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7173-51-5,N-Decyl-N,N-dimethyldecan-1-aminium chloride,as a common compound, the synthetic route is as follows.

Didecyldimethylammonium chloride (0.02 mol) was dissolved in distilled water and 0.015 mol of benzoic acid sodium salt was added. The solution was stirred at 80 C. for 7 h. The reaction mixture was extracted by chloroform. Chloroform phase was removed and washed with distilled, cold water until chloride ions were no longer detected using AgNO3. Then chloroform was removed. Obtainede benzoate in 85% yield was dried in vacuum. 1H NMR and 13C NMR (CDCl3) were obtained.

7173-51-5 N-Decyl-N,N-dimethyldecan-1-aminium chloride 23558, acatalyst-ligand compound, is more and more widely used in various.

Reference£º
Patent; Rogers, Robin D.; Daly, Daniel T.; Swatloski, Richard P.; Hough, Whitney L.; Davis, James Hilliard; Smiglak, Marcin; Pernak, Juliusz; Spear, Scott K.; US2007/93462; (2007); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI