Chemical Properties and Facts of 3393-45-1

Here is just a brief introduction to this compound(3393-45-1)Electric Literature of C5H6O2, more information about the compound(5,6-Dihydro-2H-pyran-2-one) is in the article, you can click the link below.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 3393-45-1, is researched, SMILESS is O=C1C=CCCO1, Molecular C5H6O2Journal, Organometallics called Tricyclic Sulfoxide-Alkene Hybrid Ligands for Chiral Rh(I) Complexes: The “”Matched”” Diastereomer Catalyzes Asymmetric C-C Bond Formations, Author is Nikol, Alexander; Zhang, Ziyun; Chelouan, Ahmed; Falivene, Laura; Cavallo, Luigi; Herrera, Alberto; Heinemann, Frank W.; Escalona, Ana; Friess, Sibylle; Grasruck, Alexander; Dorta, Romano, the main research direction is phenyldibenzo tropylidene deprotonation glucose butyl sulfinate rhodium catalyst; dinuclear complex DFT mol structure conjugate addition arylboronic acid; Michael acceptor asym synthesis enone Hayashi Miyaura mechanism.Electric Literature of C5H6O2.

Deprotonation of phenyldibenzo[b,f]tropylidene (I) with LDA/t-BuOK followed by quenching with either diastereomer of inexpensive glucose-based (R)- or (S)-t-Bu-sulfinate affords a sulfoxide-alkene hybrid ligand as the diastereomeric pairs (SS,SC)-II/(SS,RC)-II and (RS,RC)-II/(RS,SC)-II, resp., which via chromatog./recrystallization may be separated into the four isomers. The optically pure diastereomeric ligands (SS,SC)-II and (SS,RC)-II react with [RhCl(coe)2]2 to form the dinuclear complexes (RS,SC)-II(Rh2Cl2) and (RS,RC)-II(Rh2Cl2), resp., in which the bidentate ligands coordinate the metal centers through the sulfur and alkene donor functions. These complexes catalyze the conjugate addition of arylboronic acids to cyclic Michael acceptors with enantioselectivities of up to 99% ee. DFT calculations show the preponderant influence of planar chirality of the ligand alkene function. The enantioselectivity switch observed between (RS,SC)-II(Rh2Cl2) and (RS,RC)-II(Rh2Cl2) is explained by the inverted cis-trans coordinations of the substrate mols. in catalytic steps.

Here is just a brief introduction to this compound(3393-45-1)Electric Literature of C5H6O2, more information about the compound(5,6-Dihydro-2H-pyran-2-one) is in the article, you can click the link below.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI